{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T19:55:13Z","timestamp":1759694113022},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,3,7]],"date-time":"2014-03-07T00:00:00Z","timestamp":1394150400000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Contact dermatitis is one of the most frequent pathological manifestations of the skin and plays a central role in clinical dermatology. The <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20101 family consists a large group of cytokines, which currently contains 11 members with different pro\u2010 and anti\u2010inflammatory properties. Among the more pro\u2010inflammatory\u2010acting cytokines from the <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20101 family, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20101<jats:italic>\u03b2<\/jats:italic>,<jats:styled-content style=\"fixed-case\"> IL<\/jats:styled-content>\u201018, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201033 and <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201036 have been shown to be upregulated in different inflammatory mouse experimental models or skin diseases. The article by Mattii et\u00a0al. represents a thorough analysis of the expression of <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20101 family members including <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201033 in skin samples from patients with allergic contact dermatitis. Although a lot of research is performed in this area, data from human samples are rather scarce. Therefore, Mattii et\u00a0al. support the development of novel therapeutic concepts, which might include the use of antagonistic molecules targeting the <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20101 family network.<\/jats:p>","DOI":"10.1111\/exd.12311","type":"journal-article","created":{"date-parts":[[2013,12,21]],"date-time":"2013-12-21T00:18:12Z","timestamp":1387585092000},"page":"151-152","source":"Crossref","is-referenced-by-count":5,"title":["Allergic contact dermatitis beyond <scp>IL<\/scp>\u20101<i>\u03b2<\/i> role of additional family members"],"prefix":"10.1111","volume":"23","author":[{"given":"Margitta","family":"Worm","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy Charit\u00e9 Campus Mitte \u2013 University Medicine Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,7]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.12143_suppl"},{"key":"e_1_2_3_3_1","first-page":"167","volume":"4","author":"Veerdonk F L","year":"2013","journal-title":"Front Immunol"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12034"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1307321110"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.446"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI63451"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12027"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12076"},{"key":"e_1_2_3_10_1","first-page":"R400","volume":"273","author":"Fantuzzi G","year":"1997","journal-title":"Am J Physiol"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20112691"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200910126"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20112258"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20070157"},{"key":"e_1_2_3_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12272"},{"key":"e_1_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-202264"},{"key":"e_1_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12251"}],"container-title":["Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fexd.12311","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/exd.12311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T17:01:24Z","timestamp":1695574884000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/exd.12311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["10.1111\/exd.12311"],"URL":"https:\/\/doi.org\/10.1111\/exd.12311","archive":["Portico"],"relation":{},"ISSN":["0906-6705","1600-0625"],"issn-type":[{"value":"0906-6705","type":"print"},{"value":"1600-0625","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3]]}}}