{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T19:44:31Z","timestamp":1787600671328,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,3,28]],"date-time":"2014-03-28T00:00:00Z","timestamp":1395964800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Narrowband ultraviolet (<jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content>)<jats:styled-content style=\"fixed-case\">B<\/jats:styled-content> is accepted as corner stone therapy for vitiligo. Its influence on the expression of <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201017, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u2010 22 and <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>ox<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>3 as markers for the <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>h17 and Tregs lineages has not been studied before in the context of non\u2010segmental vitiligo (<jats:styled-content style=\"fixed-case\">NSV<\/jats:styled-content>). The study included 20 active <jats:styled-content style=\"fixed-case\">NSV<\/jats:styled-content> patients who received 36 <jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> sessions and 20 controls. Clinical evaluation <jats:styled-content style=\"fixed-case\">V<\/jats:styled-content>itiligo <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>rea <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>coring <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndex (<jats:styled-content style=\"fixed-case\">VASI<\/jats:styled-content>) and determination of tissue expression of <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201017, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201022 and <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>ox<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>3 by q<jats:styled-content style=\"fixed-case\">RT<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> (lesional, perilesional) were carried out before and after therapy. Baseline levels of <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201017 and <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201022 were significantly higher in patients, whereas <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>ox<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>3 was significantly lower. After therapy, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201017 and <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201022 significantly dropped, whereas <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>ox<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>3 significantly increased (lesional, perilesional). Baseline and post\u2010treatment <jats:styled-content style=\"fixed-case\">VASI<\/jats:styled-content> showed significant positive correlations with <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201017 and <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201022 and significant negative correlation with <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>ox<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>3 expression. Restoration of the balance between <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>h17 and <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>regs might represent a novel pathway for the improvement that <jats:styled-content style=\"fixed-case\">NB<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">UVB<\/jats:styled-content> exerts in vitiligo patients.<\/jats:p>","DOI":"10.1111\/exd.12369","type":"journal-article","created":{"date-parts":[[2014,3,11]],"date-time":"2014-03-11T14:05:09Z","timestamp":1394546709000},"page":"283-286","source":"Crossref","is-referenced-by-count":74,"title":["<scp>T<\/scp> helper 17 and <scp>T<\/scp>regs: a novel proposed mechanism for <scp>NB<\/scp>\u2010<scp>UVB<\/scp> in vitiligo"],"prefix":"10.1111","volume":"23","author":[{"given":"Rehab A.","family":"Hegazy","sequence":"first","affiliation":[{"name":"Department of Dermatology Kasr AlAini Hospital Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marwa M.","family":"Fawzy","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kasr AlAini Hospital Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heba I.","family":"Gawdat","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kasr AlAini Hospital Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nesrin","family":"Samir","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kasr AlAini Hospital Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laila A.","family":"Rashed","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Kasr AlAini Hospital Cairo University Cairo 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