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The complexity of psoriasis disease not only requires appropriate therapy but also weight\u2010loss and smoking cessation programmes as well as trigger factor elimination. The term \u2018management\u2019 may better reflect the aim for a holistic approach of disease control. Comorbidity and the presence of psoriatic arthritis are important denominators for drug selection. However, there is a lack of prospective data substantiating a benefit of associated diseases by antipsoriatic therapy. Securing success using treatment goals helps to establish an efficacious therapy and to control inflammation. A regular scoring of disease severity, patients\u2019 quality of life and assessment of other clinically relevant conditions are mandatory to closely follow the disease course. There is debate whether an early treatment may modulate the future course of psoriasis. Concepts of minimal disease activity have not been implemented in psoriasis yet. There is a lack of evidence how long any treatment should be given and when and how to terminate. Finally, outcome tools should specifically be tailored for psoriasis to evaluate disease\u2010related items as well as the benefit of management from the patient's perspective.<\/jats:p>","DOI":"10.1111\/exd.12437","type":"journal-article","created":{"date-parts":[[2014,5,11]],"date-time":"2014-05-11T09:46:49Z","timestamp":1399801609000},"page":"705-709","source":"Crossref","is-referenced-by-count":77,"title":["Psoriasis: to treat or to manage?"],"prefix":"10.1111","volume":"23","author":[{"given":"Ulrich","family":"Mrowietz","sequence":"first","affiliation":[{"name":"Psoriasis\u2010Center Department of Dermatology University Medical Center Schleswig\u2010Holstein Campus Kiel Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirsten","family":"Steinz","sequence":"additional","affiliation":[{"name":"Psoriasis\u2010Center Department of Dermatology University Medical Center Schleswig\u2010Holstein Campus Kiel 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