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Hereditary blistering diseases represent not only a disastrous fate for affected patients, but also an opportunity for understanding human molecular physiology and pathophysiology. On the basis of their clinical expertise, Gosty\u0144ski <jats:italic>et\u00a0al<\/jats:italic>. have elegantly used differences between lesional and non\u2010lesional as a unique opportunity to dissect the role of structural skin proteins \u2013 namely type <jats:styled-content style=\"fixed-case\">XVII<\/jats:styled-content> collagen, laminin <jats:italic>\u03b2<\/jats:italic>3 and type <jats:styled-content style=\"fixed-case\">VII<\/jats:styled-content> collagen \u2013 in melanocyte biology, thus elucidating a new concept in melanocyte biology by transferring knowledge in reverse direction from bedside to bench.<\/jats:p>","DOI":"10.1111\/exd.12475","type":"journal-article","created":{"date-parts":[[2014,6,24]],"date-time":"2014-06-24T16:28:55Z","timestamp":1403627335000},"page":"549-550","source":"Crossref","is-referenced-by-count":2,"title":["From bedside to bench \u2013 reverse translational medicine. 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