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Despite more complex <jats:italic>in vitro<\/jats:italic> models, we fail to explain the fundamental principles to scar formation, and the timeline of their development. The solution to developing the ideal <jats:italic>in vitro<\/jats:italic> scar model is one that mimics the heterogeneous cellular and molecular interactions, as well as the evolving structure and function of human skin.<\/jats:p>","DOI":"10.1111\/exd.12506","type":"journal-article","created":{"date-parts":[[2014,7,18]],"date-time":"2014-07-18T06:43:04Z","timestamp":1405665784000},"page":"811-812","source":"Crossref","is-referenced-by-count":6,"title":["Where we stand with human hypertrophic and keloid scar models"],"prefix":"10.1111","volume":"23","author":[{"given":"Felicia N.","family":"Williams","sequence":"first","affiliation":[{"name":"Shriners Hospital for Children and University of Texas Medical Branch Galveston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David N.","family":"Herndon","sequence":"additional","affiliation":[{"name":"Shriners Hospital for Children and University of Texas Medical Branch Galveston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ludwik K.","family":"Branski","sequence":"additional","affiliation":[{"name":"Shriners Hospital for Children and University of Texas Medical Branch Galveston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,10,29]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12419"},{"key":"e_1_2_4_3_1","author":"Ud\u2010Din S","year":"2014","journal-title":"Exp Dermatol"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2012.01476.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-009-1014-y"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0906-6705.2004.00165.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318176c4b3"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0021245"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e31828e2138"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2008.06.020"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00266-002-1121-z"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-505-7_11"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12272-012-0220-x"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.06.070"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2008.101"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00555.2001"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2010.01173.x"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-475X.2011.00736.x"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/471661a"}],"container-title":["Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fexd.12506","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fexd.12506","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/exd.12506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T08:19:28Z","timestamp":1695543568000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/exd.12506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,29]]},"references-count":18,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1111\/exd.12506"],"URL":"https:\/\/doi.org\/10.1111\/exd.12506","archive":["Portico"],"relation":{},"ISSN":["0906-6705","1600-0625"],"issn-type":[{"value":"0906-6705","type":"print"},{"value":"1600-0625","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,29]]}}}