{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T21:15:13Z","timestamp":1790111713997,"version":"4.0.1"},"reference-count":22,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2014,11,25]],"date-time":"2014-11-25T00:00:00Z","timestamp":1416873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>While the goal of available treatment in vitiligo is to regain pigmentation, some patients affected by extensive and treatment\u2010resistant vitiligo, with a major social and emotional impact, may benefit from depigmentation therapy. However, results from such therapy may not always be satisfactory. So to achieve better, faster and complete bleaching, Webb et\u00a0al. propose a synergistic approach that combines topical application of bleaching phenols which targets melanocytes and initiate local inflammation with immune adjuvants so as to obtain an enhanced immune response against remaining melanocytes. This strategy could be reliable, but should be evaluated cautiously in future studies, in terms of potential side effects and induction of undesired autoimmunity.<\/jats:p>","DOI":"10.1111\/exd.12508","type":"journal-article","created":{"date-parts":[[2014,7,18]],"date-time":"2014-07-18T07:07:54Z","timestamp":1405667274000},"page":"879-880","source":"Crossref","is-referenced-by-count":7,"title":["Accelerating bleaching in vitiligo: balancing benefits versus risks"],"prefix":"10.1111","volume":"23","author":[{"given":"Julien","family":"Seneschal","sequence":"first","affiliation":[{"name":"Department of Dermatology and Pediatric Dermatology National Centre for Rare Skin disorders, H\u00f4pital Saint\u2010Andr\u00e9 Bordeaux France"},{"name":"INSERM U1035 Bordeaux University Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katia","family":"Boniface","sequence":"additional","affiliation":[{"name":"INSERM U1035 Bordeaux University Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Ezzedine","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Pediatric Dermatology National Centre for Rare Skin disorders, H\u00f4pital Saint\u2010Andr\u00e9 Bordeaux France"},{"name":"INSERM U1035 Bordeaux University Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Taieb","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Pediatric Dermatology National Centre for Rare Skin disorders, H\u00f4pital Saint\u2010Andr\u00e9 Bordeaux France"},{"name":"INSERM U1035 Bordeaux University Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,25]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp0804388"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2010.03876.x"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12344"},{"key":"e_1_2_4_5_1","author":"Webb K C","year":"2014","journal-title":"Exp Dermatol"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2007.00666.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12372"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12161"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1998.tb05863.x"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-004-0465-4"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0109005"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3007909"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1102437"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri2358"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12219"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12309"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12264"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000354607"},{"key":"e_1_2_4_19_1","author":"Drummond A","year":"2014","journal-title":"Australas J Dermatol"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3181f2bf9e"},{"key":"e_1_2_4_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.10124.x"},{"key":"e_1_2_4_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38298"},{"key":"e_1_2_4_23_1","first-page":"1022","volume":"9","author":"Burnett T J","year":"2010","journal-title":"J Drugs Dermatol"}],"container-title":["Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fexd.12508","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/exd.12508","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T06:25:59Z","timestamp":1695536759000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/exd.12508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,25]]},"references-count":22,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1111\/exd.12508"],"URL":"https:\/\/doi.org\/10.1111\/exd.12508","archive":["Portico"],"relation":{},"ISSN":["0906-6705","1600-0625"],"issn-type":[{"value":"0906-6705","type":"print"},{"value":"1600-0625","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,25]]}}}