{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:25:08Z","timestamp":1790961908665,"version":"4.1.0"},"reference-count":90,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,11,11]],"date-time":"2014-11-11T00:00:00Z","timestamp":1415664000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Clinicians have long reported that hair\u2010bearing areas tend to heal more rapidly than those lacking hair follicles. In the past decade, numerous scientific studies have corroborated clinical evidence, showing a direct nexus between the human hair follicle and the wound healing process. The migration of epithelial follicular stem cells to the skin surface to help in the wound re\u2010epithelialization and the effect of the hair cycle on the wound healing rate underline the influence of the hair follicle in the healing process. In clinical practice, non\u2010healing wounds are pathologies of high prevalence with significant associated burden costs for the healthcare system. As the population ages, the prevalence of this pathology is expected to increase in future years. The recent advances in understanding the biology of hair follicle stem cells have created the challenges of using this newly acquired knowledge in practical therapeutic applications. Chronic leg ulcers are an example of the targeted pathologies that urgently need better therapies. In this essay, our aim is to raise interest in this question, reviewing what is known in relation to the connections between hair follicles and wound healing, and elaborating on future directions that the field might take, including implications for clinical practice.<\/jats:p>","DOI":"10.1111\/exd.12521","type":"journal-article","created":{"date-parts":[[2014,7,25]],"date-time":"2014-07-25T12:05:18Z","timestamp":1406289918000},"page":"91-94","source":"Crossref","is-referenced-by-count":58,"title":["Reflections on how wound healing\u2010promoting effects of the hair follicle can be translated into clinical practice"],"prefix":"10.1111","volume":"24","author":[{"given":"Francisco","family":"Jimenez","sequence":"first","affiliation":[{"name":"Mediteknia Dermatology Clinic Las Palmas de Gran Canaria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique","family":"Poblet","sequence":"additional","affiliation":[{"name":"Department of Pathology Hospital Universitario Reina Sof\u00eda Murcia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ander","family":"Izeta","sequence":"additional","affiliation":[{"name":"Tissue Engineering Laboratory Instituto Biodonostia Hospital Universitario Donostia San Sebasti\u00e1n 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