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These methods were applied to a set of 120 \u201cdifficult\u201d dermoscopy images of dysplastic nevi and melanomas that were subsequently excised\/classified. This approach yielded 98% sensitivity and 36% specificity for melanoma detection, approaching sensitivity\/specificity of expert lesion evaluation. Importantly, we found strong spectral dependence of many imaging biomarkers in blue or red colour channels, suggesting the need to optimize spectral evaluation of pigmented lesions.<\/jats:p>","DOI":"10.1111\/exd.13250","type":"journal-article","created":{"date-parts":[[2016,12,20]],"date-time":"2016-12-20T04:06:43Z","timestamp":1482206803000},"page":"615-618","source":"Crossref","is-referenced-by-count":27,"title":["Digital imaging biomarkers feed machine learning for melanoma screening"],"prefix":"10.1111","volume":"26","author":[{"given":"Daniel S.","family":"Gareau","sequence":"first","affiliation":[{"name":"Laboratory for Investigative Dermatology The Rockefeller University  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel","family":"Correa da Rosa","sequence":"additional","affiliation":[{"name":"Laboratory for Investigative Dermatology The Rockefeller University  New York NY USA"},{"name":"The Center for Clinical and Translational Science The Rockefeller University  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Yagerman","sequence":"additional","affiliation":[{"name":"Department of Dermatology New York University Langone Medical Center  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Carucci","sequence":"additional","affiliation":[{"name":"Department of Dermatology New York University Langone Medical Center  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Gulati","sequence":"additional","affiliation":[{"name":"Laboratory for Investigative Dermatology The Rockefeller University  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferran","family":"Hueto","sequence":"additional","affiliation":[{"name":"Massachusetts Institute of Technology Auto\u2010ID Lab  Cambridge MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer L.","family":"DeFazio","sequence":"additional","affiliation":[{"name":"Dermatology Service Memorial Sloan Kettering Cancer Center  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayte","family":"Su\u00e1rez\u2010Fari\u00f1as","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashfaq","family":"Marghoob","sequence":"additional","affiliation":[{"name":"Dermatology Service Memorial Sloan Kettering Cancer Center  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James G.","family":"Krueger","sequence":"additional","affiliation":[{"name":"Laboratory for Investigative Dermatology The Rockefeller University  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,12,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.04.021"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12032"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.09.003"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.302"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1188\/15.CJON.31-32"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/9781841847627"},{"key":"e_1_2_10_8_1","first-page":"171","volume":"2014","author":"Malvehy J.","journal-title":"Br. 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