{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:16:03Z","timestamp":1787501763203,"version":"build-2736575974"},"reference-count":16,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,7,9]],"date-time":"2017-07-09T00:00:00Z","timestamp":1499558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2010\/51729\u20102"],"award-info":[{"award-number":["2010\/51729\u20102"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2017,10]]},"abstract":"Abstract<\/jats:title>\n \n Pemphigus vulgaris (\n PV<\/jats:styled-content>\n ) and pemphigus foliaceus (\n PF<\/jats:styled-content>\n ) are blistering autoimmune diseases that depend on interaction between genetic and environmental factors. Viral infections, like herpes simplex viruses 1 and 2 (\n HSV<\/jats:styled-content>\n 1\/2), cytomegalovirus (\n CMV<\/jats:styled-content>\n ), Epstein\u2010Barr virus and dengue virus, could trigger or exacerbate pemphigus. IgM and IgG antibodies against these viruses in serum from\n PV<\/jats:styled-content>\n and\n PF<\/jats:styled-content>\n , their relatives and controls were determined.\n HSV<\/jats:styled-content>\n 1\/2 expression was evaluated by direct immunofluorescence (\n DIF<\/jats:styled-content>\n ) and\n qPCR<\/jats:styled-content>\n in affected or not oral mucosa from\n PV<\/jats:styled-content>\n patients compared with uninjured\n PF<\/jats:styled-content>\n mucosa. IgG anti\u2010\n HSV<\/jats:styled-content>\n 1 was higher in the\n PV<\/jats:styled-content>\n group compared with all groups. IgG anti\u2010\n CMV<\/jats:styled-content>\n resulted higher in\n PV<\/jats:styled-content>\n group compared with\n PF<\/jats:styled-content>\n patients and\n PV<\/jats:styled-content>\n relatives.\n HSV<\/jats:styled-content>\n 1 was confirmed by\n DIF<\/jats:styled-content>\n and\n qPCR<\/jats:styled-content>\n on oral samples from patients with\n PV<\/jats:styled-content>\n . Lack of\n HSV<\/jats:styled-content>\n 1 expression in the oral mucosa of patients with\n PF<\/jats:styled-content>\n corroborate that immunosuppressive therapy cannot be the main cause for\n HSV<\/jats:styled-content>\n 1 replication in\n PV<\/jats:styled-content>\n disease.\n <\/jats:p>","DOI":"10.1111\/exd.13342","type":"journal-article","created":{"date-parts":[[2017,3,31]],"date-time":"2017-03-31T03:23:00Z","timestamp":1490930580000},"page":"966-968","source":"Crossref","is-referenced-by-count":21,"title":["Herpes simplex virus 1 and cytomegalovirus are associated with pemphigus vulgaris but not with pemphigus foliaceus disease"],"prefix":"10.1111","volume":"26","author":[{"given":"Aline Rafaela da Silva Rodrigues","family":"Machado","sequence":"first","affiliation":[{"name":"Division of Dermatology Department of Medical Clinics Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo Ribeirao Preto S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"La Serra","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medical Clinics Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo Ribeirao Preto S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline","family":"Turatti","sequence":"additional","affiliation":[{"name":"Laboratory of Dermatology University Hospital Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo Ribeirao Preto S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex Martins","family":"Machado","sequence":"additional","affiliation":[{"name":"Tres Lagoas Medical School Federal University of Mato Grosso do Sul Tr\u00eas Lagoas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2709-1825","authenticated-orcid":false,"given":"Ana Maria","family":"Roselino","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medical Clinics Ribeir\u00e3o Preto Medical School University of S\u00e3o Paulo Ribeirao Preto S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,9]]},"reference":[{"key":"e_1_2_2_2_1","author":"Di Zenzo G","year":"2016","journal-title":"Exp. Dermatol"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13106"},{"key":"e_1_2_2_4_1","author":"Furue M.","year":"2017","journal-title":"Australas J Dermatol."},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-015-0541-1"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13026"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-7310(09)73377-0"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2016.07.005"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2016.04.007"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dib.2016.05.077"},{"key":"e_1_2_2_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000365845"},{"key":"e_1_2_2_12_1","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1684\/ejd.2012.1836","volume":"22","author":"Senger P.","year":"2012","journal-title":"Eur. J. Dermatol."},{"key":"e_1_2_2_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12961"},{"key":"e_1_2_2_14_1","first-page":"6","volume":"17","author":"Galarza Manyari C","year":"2006","journal-title":"Folia Dermatol. Peru"},{"key":"e_1_2_2_15_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962011000600007"},{"key":"e_1_2_2_16_1","author":"Senger P","year":"2017","journal-title":"Eur. J. Dermatol."},{"key":"e_1_2_2_17_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102-311X2011000900014"}],"container-title":["Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fexd.13342","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/exd.13342","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T10:18:39Z","timestamp":1695550719000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/exd.13342"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,9]]},"references-count":16,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["10.1111\/exd.13342"],"URL":"https:\/\/doi.org\/10.1111\/exd.13342","archive":["Portico"],"relation":{},"ISSN":["0906-6705","1600-0625"],"issn-type":[{"value":"0906-6705","type":"print"},{"value":"1600-0625","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,9]]}}}