{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T14:38:36Z","timestamp":1785767916773,"version":"3.56.0"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,6,13]],"date-time":"2017-06-13T00:00:00Z","timestamp":1497312000000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In addition to genetics and androgens, novel factors could play a role in androgenetic alopecia (<jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content>). This study aims to investigate the association between plasma leptin level with the risk and severity of <jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content> in men. Forty\u2010eight subjects were enrolled including 29 <jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content> and 19 non\u2010<jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content> subjects. The plasma leptin level was significantly higher in <jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content> subjects, compared to non\u2010<jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content> subjects (4.45 vs 2.76\u00a0ng\/<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>,<jats:italic> P<\/jats:italic>&lt;.05). A higher plasma leptin levels were positively correlated with the risk of developing <jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content> in multivariate logistic analysis (odds ratio=2.77, <jats:italic>P<\/jats:italic>&lt;.05). Leptin from the circulation might impact the development of <jats:styled-content style=\"fixed-case\">AGA<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/exd.13369","type":"journal-article","created":{"date-parts":[[2017,4,19]],"date-time":"2017-04-19T16:28:58Z","timestamp":1492619338000},"page":"524-526","source":"Crossref","is-referenced-by-count":12,"title":["Higher plasma leptin is associated with higher risk of androgenetic alopecia in men"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3897-6522","authenticated-orcid":false,"given":"Chao\u2010Chun","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Dermatology National Cheng Kung University Hospital, College of Medicine National Cheng Kung University  Tainan Taiwan"},{"name":"International Research Center for Wound Repair and Regeneration National Cheng Kung University  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei\u2010Lun","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Dermatology National Cheng Kung University Hospital, College of Medicine National Cheng Kung University  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li\u2010Yu","family":"Lin","sequence":"additional","affiliation":[{"name":"Yuan's Dermatology Clinic  Taichung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael W.","family":"Hughes","sequence":"additional","affiliation":[{"name":"International Research Center for Wound Repair and Regeneration National Cheng Kung University  Tainan Taiwan"},{"name":"Institute of Clinical Medicine, National Cheng Kung University Hospital, College of Medicine National Cheng Kung University  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yau\u2010Sheng","family":"Tsai","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, National Cheng Kung University Hospital, College of Medicine National Cheng Kung University  Tainan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,6,13]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12965"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.09.036"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2014.10.015"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12566"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12286"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/789653"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2002.00613.x"},{"key":"e_1_2_3_9_1","author":"Castela M.","year":"2017","journal-title":"Exp. 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