{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T06:26:08Z","timestamp":1782368768927,"version":"3.54.5"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,8,15]],"date-time":"2017-08-15T00:00:00Z","timestamp":1502755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Rosacea is a chronic inflammatory dermatosis affecting the face and eyes. An association between systemic comorbidities and rosacea has been reported, but the link to enteral microbiota is uncertain. We aimed to investigate the link between rosacea and enteral microbiota. A cross\u2010sectional study was performed in a sample of Korean women who participated in a health check\u2010up programme at the Kangbuk Samsung Hospital Health Screening Center between 23 June 2014 and 5 September 2014. The gut microbiome was evaluated by 16S <jats:styled-content style=\"fixed-case\">rRNA<\/jats:styled-content> gene and metagenome sequence analyses. A total of 12 rosacea patients and 251 controls were enrolled. We identified links between rosacea and several changes in gut microbiota: reduced abundance of <jats:italic>Peptococcaceae family unknown genus<\/jats:italic>,<jats:italic> Methanobrevibacter<\/jats:italic> (genus)<jats:italic>, Slackia<\/jats:italic> (genus)<jats:italic>, Coprobacillus<\/jats:italic> (genus)<jats:italic>, Citrobacter<\/jats:italic> (genus), and <jats:italic>Desulfovibrio<\/jats:italic> (genus), and increased abundance of <jats:italic>Acidaminococcus<\/jats:italic> (genus)<jats:italic>, Megasphaera<\/jats:italic> (genus)<jats:italic>,<\/jats:italic> and <jats:italic>Lactobacillales order unknown family unknown<\/jats:italic> genus. A link between rosacea and enteral microbiota was observed in this metagenomic study. A large and elaborate study is needed to confirm these findings and to elucidate the mechanisms involved.<\/jats:p>","DOI":"10.1111\/exd.13398","type":"journal-article","created":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T20:06:55Z","timestamp":1498075615000},"page":"37-42","source":"Crossref","is-referenced-by-count":74,"title":["Rosacea and its association with enteral microbiota in Korean females"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4760-7390","authenticated-orcid":false,"given":"Jae\u2010Hui","family":"Nam","sequence":"first","affiliation":[{"name":"Department of Dermatology Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeojun","family":"Yun","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Ewha Womans University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han\u2010Saem","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han\u2010Na","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Ewha Womans University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho Joo","family":"Jung","sequence":"additional","affiliation":[{"name":"Good Dermatologic Clinic  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoosoo","family":"Chang","sequence":"additional","affiliation":[{"name":"Center for Cohort Studies Total Healthcare Center Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"},{"name":"Department of Occupational and Environmental Medicine Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"},{"name":"Department of Clinical Research Design &amp; Evaluation SAIHST Sungkyunkwan University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seungho","family":"Ryu","sequence":"additional","affiliation":[{"name":"Center for Cohort Studies Total Healthcare Center Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"},{"name":"Department of Occupational and Environmental Medicine Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"},{"name":"Department of Clinical Research Design &amp; Evaluation SAIHST Sungkyunkwan University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hocheol","family":"Shin","sequence":"additional","affiliation":[{"name":"Center for Cohort Studies Total Healthcare Center Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"},{"name":"Department of Family Medicine Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyung\u2010Lae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Biochemistry Ewha Womans University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won\u2010Serk","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Dermatology Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp042829"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.04.045"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17091562"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.417"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.21"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.01.016"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1101\/gr.131029.111"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0002719"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.08.021"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2009.01060.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1128\/AAC.02531-15","volume":"60","author":"Citron D. 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