{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T05:09:45Z","timestamp":1776402585282,"version":"3.51.2"},"reference-count":9,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T00:00:00Z","timestamp":1515456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this study, we investigated how tannic acid (<jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content>) protects the skin from inflammation caused by external irritation. The effects of <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content> were evaluated using a mouse 12\u2010<jats:italic>O<\/jats:italic>\u2010tetradecanoylphorbol 13\u2010acetate (<jats:styled-content style=\"fixed-case\">TPA<\/jats:styled-content>)\u2010induced skin inflammation model and a reconstructed human epidermal model. We then used Lucifer Yellow for visual confirmation of <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content>'s suppression effect at the stratum corneum (<jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content>) surface. <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content> treatment of the skin prevented Lucifer Yellow from permeating the skin. This result suggests that <jats:styled-content style=\"fixed-case\">TA<\/jats:styled-content> acts as a barrier against external stimulants such as <jats:styled-content style=\"fixed-case\">TPA<\/jats:styled-content> and artificial sweat on the <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content> surface.<\/jats:p>","DOI":"10.1111\/exd.13478","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T17:09:09Z","timestamp":1512580149000},"page":"824-826","source":"Crossref","is-referenced-by-count":12,"title":["Effect of tannic acid on skin barrier function"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4362-0616","authenticated-orcid":false,"given":"Tomoya","family":"Nakamura","sequence":"first","affiliation":[{"name":"Department of R&amp;D Center Ikeda Mohando Co., Ltd  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Department of R&amp;D Center Ikeda Mohando Co., Ltd  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsue","family":"Yasoshima","sequence":"additional","affiliation":[{"name":"Department of R&amp;D Center Ikeda Mohando Co., Ltd  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiko","family":"Kojima","sequence":"additional","affiliation":[{"name":"Department of R&amp;D Center Ikeda Mohando Co., Ltd  Toyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2007.09.009"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-017-1728-1"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.110.124453"},{"key":"e_1_2_9_5_1","first-page":"1068","volume":"19","author":"Lopetuso L. R.","year":"2015","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2012.10.019"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12964"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.51"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2014.259"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0846.2000.006004230.x"}],"container-title":["Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fexd.13478","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/exd.13478","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T16:03:57Z","timestamp":1694275437000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/exd.13478"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,9]]},"references-count":9,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["10.1111\/exd.13478"],"URL":"https:\/\/doi.org\/10.1111\/exd.13478","archive":["Portico"],"relation":{},"ISSN":["0906-6705","1600-0625"],"issn-type":[{"value":"0906-6705","type":"print"},{"value":"1600-0625","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,9]]}}}