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Unfortunately, by the time patients seek clinical evaluation of their hair loss, the skin is already inflamed and\/or scarred, so there is little hope for a return to their normal hair growth pattern. Clinical and basic science investigations are now focusing on three forms of human <jats:styled-content style=\"fixed-case\">PCA<\/jats:styled-content>: lichen planopilaris (<jats:styled-content style=\"fixed-case\">LPP<\/jats:styled-content>), frontal fibrosing alopecia (<jats:styled-content style=\"fixed-case\">FFA<\/jats:styled-content>) and central centrifugal cicatricial alopecia (<jats:styled-content style=\"fixed-case\">CCCA<\/jats:styled-content>). Transcriptome, lipidome and other new technologies are providing new insight into the pathogenesis of some of these diseases that are being validated and further investigated using spontaneous and genetically engineered mouse models.<\/jats:p>","DOI":"10.1111\/exd.13495","type":"journal-article","created":{"date-parts":[[2018,1,16]],"date-time":"2018-01-16T23:36:44Z","timestamp":1516145804000},"page":"302-310","source":"Crossref","is-referenced-by-count":25,"title":["Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1523-5430","authenticated-orcid":false,"given":"John P.","family":"Sundberg","sequence":"first","affiliation":[{"name":"The Jackson Laboratory  Bar Harbor ME USA"},{"name":"Department of Dermatology Vanderbilt University Medical Center  Nashville TN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria K.","family":"Hordinsky","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of Minnesota  Minneapolis MN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilma","family":"Bergfeld","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Pathology Cleveland Clinic  Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yolanda M.","family":"Lenzy","sequence":"additional","affiliation":[{"name":"Lenzy Dermatology &amp; Hair Loss Center  Chicopee MA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy J.","family":"McMichael","sequence":"additional","affiliation":[{"name":"Wake Forest Baptist Medical Center  Winston\u2010Salem NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela M.","family":"Christiano","sequence":"additional","affiliation":[{"name":"Department of Dermatology Columbia University College of Physicians &amp; Surgeons  New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy","family":"McGregor","sequence":"additional","affiliation":[{"name":"Clinical Genetics Vanderbilt University Medical Center  Nashville TN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurt S.","family":"Stenn","sequence":"additional","affiliation":[{"name":"Princeton NJ USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raja K.","family":"Sivamani","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of California, Davis  Sacramento CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig Herbert","family":"Pratt","sequence":"additional","affiliation":[{"name":"The Jackson Laboratory  Bar Harbor ME USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Lloyd E.","family":"King","sequence":"additional","affiliation":[{"name":"Department of Dermatology Vanderbilt University Medical Center  Nashville TN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12166.x"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2008.00203.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ad.2014.06.016"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.12788\/j.sder.2015.0133"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.12788\/j.sder.2015.0130"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000467395"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.01.056"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.09.058"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.4233"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2008.369"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14535"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13104"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.135.8.973"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0560.2001.028009445.x"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(92)70290-V"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-199908000-00003"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.07.055"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.12725"},{"key":"e_1_2_11_20_1","first-page":"32984","volume":"0022","author":"Sardella C.","year":"2017","journal-title":"J. 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