{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T04:23:58Z","timestamp":1772511838985,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T00:00:00Z","timestamp":1533254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Research Foundation at Department of Dermatology, Zealand University Hospital; Roskilde"},{"name":"The Foundation for Promotion of Research for clinical professors employed by Region Zealand and University of Copenhagen."}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Dynamic optical coherence tomography (D\u2010<jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content>) is a non\u2010invasive imaging technique, suitable for the study of structural and dynamic features of cutaneous microvasculature. Studies with D\u2010<jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content> have primarily focused on non\u2010melanoma skin cancer (<jats:styled-content style=\"fixed-case\">NMSC<\/jats:styled-content>), and a reference description of healthy skin is lacking. The aim of the study was to describe the prevalence of standard microvascular features in normal skin. A total of 280 participants without skin disease were D\u2010<jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content>\u2013scanned on four body locations: three sun\u2010exposed areas and one unexposed: forehead, back of the neck, back of the hand and medial side of the upper arm. Frequencies of standard vascular features were reported, and relations to anatomical location and demographic data were investigated. \u201cDots,\u201d \u201clines\u201d and \u201ccurves\u201d were the most frequent shapes at 150\u00a0\u03bcm, 300\u00a0\u03bcm and 500\u00a0\u03bcm. \u201cMottle\u201d was the predominant pattern at 150\u00a0\u03bcm and 300\u00a0\u03bcm. \u201cMesh\u201d was found from 300\u00a0\u03bcm and primarily found at 500\u00a0\u03bcm. Regional differences in vascular characteristics were primarily found comparing the medial side of the arm with the other body locations. In normal skin, the most frequent shapes were \u201cdots,\u201d \u201clines\u201d and \u201ccurves,\u201d and \u201cmottle\u201d was present more superficially than \u201cmesh.\u201d In conclusion, regional anatomical differences should be taken into account when evaluating D\u2010<jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content> images.<\/jats:p>","DOI":"10.1111\/exd.13680","type":"journal-article","created":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T13:21:45Z","timestamp":1525699305000},"page":"966-972","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Vascular morphology in normal skin studied with dynamic optical coherence tomography"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0132-4715","authenticated-orcid":false,"given":"Pernille","family":"Linds\u00f8 Andersen","sequence":"first","affiliation":[{"name":"Department of Dermatology Zealand University Hospital  Roskilde Denmark"},{"name":"Health Sciences Faculty University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1086-6265","authenticated-orcid":false,"given":"Jonas","family":"Olsen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Zealand University Hospital  Roskilde Denmark"},{"name":"Health Sciences Faculty University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kersti Brosb\u00f8l Engelund","family":"Friis","sequence":"additional","affiliation":[{"name":"Department of Dermatology Zealand University Hospital  Roskilde Denmark"},{"name":"Health Sciences Faculty University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1368-1522","authenticated-orcid":false,"given":"Lotte","family":"Themstrup","sequence":"additional","affiliation":[{"name":"Department of Dermatology Zealand University Hospital  Roskilde Denmark"},{"name":"Health Sciences Faculty University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kasper","family":"Grandahl","sequence":"additional","affiliation":[{"name":"Health Sciences Faculty University of Copenhagen  Copenhagen Denmark"},{"name":"Department of Occupational Medicine Copenhagen University Hospital  Holb\u00e6k Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4655-8048","authenticated-orcid":false,"given":"Ole Steen","family":"Mortensen","sequence":"additional","affiliation":[{"name":"Health Sciences Faculty University of Copenhagen  Copenhagen Denmark"},{"name":"Department of Occupational Medicine Copenhagen University Hospital  Holb\u00e6k Denmark"},{"name":"Department of Public Health, Section of Social Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0712-2540","authenticated-orcid":false,"given":"Gregor Borut Ernst","family":"Jemec","sequence":"additional","affiliation":[{"name":"Department of Dermatology Zealand University Hospital  Roskilde Denmark"},{"name":"Health Sciences Faculty University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-017-0175-4"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1087-0024.2000.00010.x"},{"key":"e_1_2_9_4_1","first-page":"817","volume-title":"Biochemistry and Physiology of the Skin","author":"Ryan T. 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