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Cav\u20101 strongly interacts with such well\u2010recognized etiopathogenic factors such as hyperseborrhea, follicular hyperkeratinization and pathogenicity of\n                    <jats:italic>Cutibacterium acnes<\/jats:italic>\n                    . Cav\u20101 is a strong negative regulator of transforming growth factor beta (TGF\u2010\u03b2) expression. It acts as a critical determinant of autophagy, which is significantly induced in acne lesions through\n                    <jats:italic>C.\u00a0acnes<\/jats:italic>\n                    and by absorption of fatty acids. Cav\u20101 also demonstrates different correlations with the development of innate immunity. We propose that normalization of Cav\u20101 expression can serve as a target in anti\u2010acne therapy.\n                  <\/jats:p>","DOI":"10.1111\/exd.14063","type":"journal-article","created":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T08:20:46Z","timestamp":1574756446000},"page":"177-183","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Caveolin\u20101 as a possible target in  the treatment for acne"],"prefix":"10.1111","volume":"29","author":[{"given":"Ilja L.","family":"Kruglikov","sequence":"first","affiliation":[{"name":"Scientific Department Wellcomet GmbH Karlsruhe Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0680-3392","authenticated-orcid":false,"given":"Philipp E.","family":"Scherer","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Touchstone Diabetes Center University of Texas Southwestern Medical Center Dallas TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,9]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"25","volume":"2017","author":"Chang C. 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