{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:06:18Z","timestamp":1747184778141,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,4,20]],"date-time":"2020-04-20T00:00:00Z","timestamp":1587340800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Scientific Research Foundation-Flanders","award":["1504718N"],"award-info":[{"award-number":["1504718N"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Vitiligo is a common chronic depigmenting skin disease. We explored the utility of near\u2010infrared (NIR) spectroscopy in the identification of spectral changes associated with disease activity in vitiligo patients. In vivo spectral measurements were performed directly on the perilesional skin of 70 vitiligo patients. Relative intensities (second derivative) at 1139, 1344, 1646 and 1839\u00a0nm appeared to be significantly lower in the perilesional region of patients with active vitiligo compared with stable disease, while the intensity at 1884\u00a0nm seemed to be significantly higher. A classification model based on the spectral ranges around those peaks generated a correct prediction in 82.9% of the cases. In conclusion, we can state that NIR spectroscopy could have potential in the assessment of disease activity. However, large\u2010scale prospective studies are necessary to confirm our preliminary results.<\/jats:p>","DOI":"10.1111\/exd.14097","type":"journal-article","created":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T12:29:50Z","timestamp":1586348990000},"page":"570-574","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Near\u2010infrared spectroscopy as a potential non\u2010invasive tool in the assessment of disease activity in vitiligo patients"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9041-4404","authenticated-orcid":false,"given":"Sander","family":"De Bruyne","sequence":"first","affiliation":[{"name":"Department of Clinical Chemistry Ghent University Ghent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinhart","family":"Speeckaert","sequence":"additional","affiliation":[{"name":"Department of Dermatology Ghent University Hospital Ghent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonas","family":"Himpe","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry Ghent University Ghent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5702-6792","authenticated-orcid":false,"given":"Joris R.","family":"Delanghe","sequence":"additional","affiliation":[{"name":"Department of Clinical Chemistry Ghent University Ghent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,4,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.01.033"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12763"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-017-0298-5"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-018-3168-4"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2015.05.003"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2009.02.004"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8071022"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.18.3.037006"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408363.2017.1414142"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4AN00483C"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.09.034"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1366\/000370206775382866"},{"key":"e_1_2_11_14_1","first-page":"969217","volume":"22","author":"Greve T. 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