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Given these rising rates, preventative measures have become increasingly important to reduce the incidence and promote early detection of these cancers. Skin cancer prevention remains a challenging task to accomplish mainly due to the lack of reliable and sensitive methods to provide objective risk information that can educate and motivate individuals to avoid sunburn. Currently, minimal erythema dose (MED) is used as a marker of UVR. However, it is not an ideal marker because significant cancer\u2010related molecular damage can occur after UVR exposure that cannot be detected by MED. Thus, over the recent years there has been significant interest in development of biomarkers indicative of exposure to UVR to improve early detection of cutaneous malignancies. Here, we will discuss emerging biomarkers for melanoma and NMSC that can help with risk stratification and targeted prevention and treatment.<\/jats:p>","DOI":"10.1111\/exd.14114","type":"journal-article","created":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T15:07:12Z","timestamp":1589641632000},"page":"4-12","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Biomarkers in melanoma and non\u2010melanoma skin cancer prevention and risk stratification"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7330-1627","authenticated-orcid":false,"given":"Megan H.","family":"Trager","sequence":"first","affiliation":[{"name":"Department of Dermatology Columbia University Irving Medical Center New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larisa J.","family":"Geskin","sequence":"additional","affiliation":[{"name":"Department of Dermatology Columbia University Irving Medical Center New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faramarz H.","family":"Samie","sequence":"additional","affiliation":[{"name":"Department of Dermatology Columbia University Irving Medical Center New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7245-355X","authenticated-orcid":false,"given":"Liang","family":"Liu","sequence":"additional","affiliation":[{"name":"The Hormel Institute University of Minnesota Austin MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,8]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Key Statistics for Melanoma Skin Cancer.https:\/\/www.cancer.org\/cancer\/melanoma\u2010skin\u2010cancer\/about\/key\u2010statistics.html(accessed: February 22 2020)"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2015.1187"},{"key":"e_1_2_9_4_1","unstructured":"Prevention CfDCa.Morbidity and Mortality Weekly Report: Sunburn and Sun Protective Behaviors Among Adults Aged 18\u201029 Years \u2014 United States 2000\u20102010. 2012; Volume 61. 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