{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T02:22:31Z","timestamp":1774146151376,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T00:00:00Z","timestamp":1645056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Cutibacterium acnes<\/jats:italic> (<jats:italic>C.\u00a0acnes<\/jats:italic>) is an organism implicated in the pathogenesis of acne. Despite regular immersion in antimicrobial chlorine, adolescent swimmers suffer from acne and tend to be resistant to standard therapies. Given the presence of <jats:italic>Pseudomonas<\/jats:italic> within swimming facilities, we hypothesized that \u201cswimmer acne\u201d is potentially driven by a different microbial mechanism. In this study, we aimed to examine the microbial dynamics of <jats:italic>C.\u00a0acnes<\/jats:italic> and Pseudomonadaceae, a family of gram\u2010negative bacteria (includes <jats:italic>Pseudomonas aeruginosa<\/jats:italic>), in swimmers and its potential contribution to the pathogenesis of acne in this population. Using fluorescence photography that measures the Coproporphyrin III (CPIII), we quantitated an absolute abundance of <jats:italic>C.\u00a0acnes<\/jats:italic> present on the face of each participant pre\u2010 and post\u2010swimming. In addition, 16S rRNA gene sequencing was utilized to assess relative abundance of the skin microbiota on each participant pre\u2010 and post\u2010swimming. 16\u00a0swimmers (8\u00a0girls and 8 boys) completed the study. Seven had acne on the face. The CPIII fluorescence levels decreased for all swimmers after 1\u00a0h of swimming (<jats:italic>p<\/jats:italic>\u2010value &lt;0.001). In contrast, the relative abundance of <jats:italic>C.\u00a0acnes<\/jats:italic> remained unchanged, while that of Pseudomonadaceae increased after swimming (<jats:italic>p<\/jats:italic>\u2010value =0.027). Comparing the relative abundances of Pseudomonadaceae before swimming, there was a significant increase in variance from the mean in acne group as compared to no acne group (<jats:italic>p<\/jats:italic>\u2010value &lt;0.001). Taken together, we conclude that the skin dysbiosis resulting from repeated decolonization and colonization of <jats:italic>C<\/jats:italic>.\u00a0acnes and Pseudomonadaceae, respectively, can potentially be associated with the pathogenesis of acne in swimmers.<\/jats:p>","DOI":"10.1111\/exd.14535","type":"journal-article","created":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T08:28:30Z","timestamp":1643963310000},"page":"899-905","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Yin and Yang of skin microbiota in \u201cswimmer acne\u201d"],"prefix":"10.1111","volume":"31","author":[{"given":"Peyton C.","family":"Morss\u2010Walton","sequence":"first","affiliation":[{"name":"University of Massachusetts Medical School  Worcester Massachusetts USA"},{"name":"Clinical Laboratory for Epidemiology and Applied Research in Skin (CLEARS) Beth Israel Deaconess Medical Center  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean S.","family":"McGee","sequence":"additional","affiliation":[{"name":"Clinical Laboratory for Epidemiology and Applied Research in Skin (CLEARS) Beth Israel Deaconess Medical Center  Boston Massachusetts USA"},{"name":"Department of Dermatology Beth Israel Deaconess Medical Center  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Rosales Santillan","sequence":"additional","affiliation":[{"name":"Clinical Laboratory for Epidemiology and Applied Research in Skin (CLEARS) Beth Israel Deaconess Medical Center  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ranch","family":"Kimball","sequence":"additional","affiliation":[{"name":"Clinical Laboratory for Epidemiology and Applied Research in Skin (CLEARS) Beth Israel Deaconess Medical Center  Boston Massachusetts 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B.","family":"Kimball","sequence":"additional","affiliation":[{"name":"Clinical Laboratory for Epidemiology and Applied Research in Skin (CLEARS) Beth Israel Deaconess Medical Center  Boston Massachusetts USA"},{"name":"Department of Dermatology Beth Israel Deaconess Medical Center  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13462"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13296"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.29"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1979.04010100023009"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.04.004"},{"issue":"48","key":"e_1_2_10_7_1","first-page":"1087","article-title":"Pseudomonas dermatitis\/folliculitis associated with 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