{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T15:42:45Z","timestamp":1773675765727,"version":"3.50.1"},"reference-count":7,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T00:00:00Z","timestamp":1694822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T00:00:00Z","timestamp":1694822400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2023,11]]},"abstract":"Abstract<\/jats:title>\n \n The appearance of actinic lentigines mainly found on face, back of the hands, upper back and d\u00e9collet\u00e9 is associated with chronic sun exposure. However, there is no study looking at the role of long UVA specifically in the development of actinic lentigines. This study was conducted in 20 Japanese adult women exposed on the upper back area three times per week for 6\u2009weeks to incremental sub\u2010erythemal UVA1 doses (5\u2009J\/cm\n 2<\/jats:sup>\n at weeks 1 and 2, 10\u2009J\/cm\n 2<\/jats:sup>\n at weeks 3 and 4 and 15\u2009J\/cm\n 2<\/jats:sup>\n at weeks 5 and 6). Clinical assessment, performed on day 0 (before any exposure), and on days 14, 28 and 42, included the evaluation of skin pigmentation (pigmented spots), chromametry of the pigmented skin lesions and measurement of dyschromy. The number of pigmented spots and uniformity of the skin's pigmentation were clearly increased in comparison with baseline, statistical significance of the difference (\n p<\/jats:italic>\n \u2009<\u20090.05) being reached at D 28 and D 42 in both cases. In conclusion, repeated sub\u2010erythemal UVA1 exposure induces the development of actinic lentigines. Thus, a suitable protection including long UVA coverage is also needed to prevent from the damages induced by low, sub\u2010erythemal doses of UV exposure.\n <\/jats:p>","DOI":"10.1111\/exd.14937","type":"journal-article","created":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T04:05:45Z","timestamp":1694837145000},"page":"2034-2037","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Development of actinic lentigines due to multiple sub\u2010erythemal exposure to\n UVA1<\/scp>\n radiation in Asian skin"],"prefix":"10.1111","volume":"32","author":[{"given":"Akimichi","family":"Morita","sequence":"first","affiliation":[{"name":"Department of Geriatric and Environmental Dermatology Nagoya City University Graduate School of Medical Sciences Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Seit\u00e9","sequence":"additional","affiliation":[{"name":"La Roche\u2010Posay Laboratoire Dermatologique Levallois\u2010Perret France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guenaelle","family":"Le\u00a0Dantec","sequence":"additional","affiliation":[{"name":"La Roche\u2010Posay Laboratoire Dermatologique Levallois\u2010Perret France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delphine","family":"Kerob","sequence":"additional","affiliation":[{"name":"La Roche\u2010Posay Laboratoire Dermatologique Levallois\u2010Perret France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1011-1344(98)00182-1"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.1999.tb03273.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0749.2004.00131.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.116.5.1208"},{"key":"e_1_2_10_6_1","volume-title":"Photo\u2010Aging Face & Body","author":"Flament F","year":"2017"},{"key":"e_1_2_10_7_1","volume-title":"Protection of the Skin against Ultraviolet Radiations","author":"Rougier A","year":"1998"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23158243"}],"container-title":["Experimental Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/exd.14937","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/exd.14937","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/exd.14937","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T10:49:02Z","timestamp":1771152542000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/exd.14937"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,16]]},"references-count":7,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1111\/exd.14937"],"URL":"https:\/\/doi.org\/10.1111\/exd.14937","archive":["Portico"],"relation":{},"ISSN":["0906-6705","1600-0625"],"issn-type":[{"value":"0906-6705","type":"print"},{"value":"1600-0625","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,16]]},"assertion":[{"value":"2023-08-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}