{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T09:38:16Z","timestamp":1787737096475,"version":"build-2784847793"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,3,20]],"date-time":"2025-03-20T00:00:00Z","timestamp":1742428800000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Genital involvement and sexual dysfunction are common amongst patients with psoriasis. However, the effects of genital psoriasis on quality of life (QOL) and sexual health of psoriasis patients are not well understood. We performed an observational study on adult Asian psoriasis patients attending psoriasis subspecialty clinics in a tertiary dermatology centre in Singapore over 1\u2009year. Participants underwent clinical examination of the whole\u2010body surface, with particular attention to the genitalia and questionnaires to evaluate QOL and psychosexual health were administered. A total of 62 patients participated. Most participants were male (82.3%) with a mean age of 41.7\u2009years (SD 12.5). The mean Psoriasis Area and Severity Index (PASI) score was 7.0 (SD 4.3) with a mean Dermatology Life Quality Index (DLQI) score of 9.8 (SD 6.7), indicating moderately impaired QOL. Higher PASI scores were associated with increasing QOL impairment on DLQI (<jats:italic>p<\/jats:italic>\u2009=\u20090.021). The commonest site involved was the suprapubic region (61.3%). Males in whom genital psoriasis prevented sexual intercourse or diminished their libido reported more sexual dysfunction. Females reported a greater severity impact of genital psoriasis in terms of symptoms and embarrassment (<jats:italic>p<\/jats:italic>\u2009=\u20090.038) yet were less likely to be on treatment (37.5% vs. 45.0%). Perceived efficacy of treatment was low, and younger patients fared poorly on the Patient Health Questionnaire\u20109 depression questionnaire (<jats:italic>p<\/jats:italic>\u2009=\u20090.047). Clinicians should proactively evaluate for and treat genital psoriasis, as patients may be reluctant to discuss their genital rashes if not prompted, leading to under\u2010recognition and undertreatment.<\/jats:p>","DOI":"10.1111\/exd.70072","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T05:17:15Z","timestamp":1742534235000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Genital Psoriasis in Asians: Impact on Quality of Life and Sexual Health"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3795-2657","authenticated-orcid":false,"given":"Kim Yao","family":"Ong","sequence":"first","affiliation":[{"name":"National Skin Centre Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yee Kiat","family":"Heng","sequence":"additional","affiliation":[{"name":"National Skin Centre Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiahong","family":"Zhao","sequence":"additional","affiliation":[{"name":"National Skin Centre Singapore City Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7607-3124","authenticated-orcid":false,"given":"Hazel H.","family":"Oon","sequence":"additional","affiliation":[{"name":"National Skin Centre Singapore City Singapore"},{"name":"Yong Loo Lin School of Medicine National University of Singapore Singapore City Singapore"},{"name":"Lee Kong Chian School of Medicine Singapore city Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,20]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(20)32549\u20106"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2018.1453125"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000338858"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555\u20100372"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.12.1493"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.186"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.2147\/PTT.S169389"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102230.2012.04457.x"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20104362.1997.00032.x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102133.2011.10249.x"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001050050635"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102230.1994.tb01167.x"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12978\u2010022\u201001403\u2010z"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.2147\/PTT.S159916"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.4081\/monaldi.2013.5234"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00926230290001448"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/00926230590475206"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525\u20101497.2001.016009606.x"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.5114\/reum.2018.80718"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2017.09.005"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.11622\/smedj.2019152"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600799"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555\u20101885"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1155\/2024\/7006796"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.ijd_754_21"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555\u2010018\u20100257\u2010y"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2018.1448788"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555\u2010017\u20100212\u20103"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555\u2010017\u20100213\u20102"}],"container-title":["Experimental 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