{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T16:12:50Z","timestamp":1789488770124,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T00:00:00Z","timestamp":1767398400000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62105197"],"award-info":[{"award-number":["62105197"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFC2510800"],"award-info":[{"award-number":["2024YFC2510800"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Experimental Dermatology"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The Mueller matrix has the capability of providing the complete polarisation information about the response of a medium to the incident polarised light. In this work, we report that the anisotropic structures of non\u2010stained melanoma slices can be identified directly through the Mueller elements. It is observed that the elements M\n                    <jats:sub>12<\/jats:sub>\n                    , M\n                    <jats:sub>22<\/jats:sub>\n                    and M\n                    <jats:sub>24<\/jats:sub>\n                    show a high degree of similarity with the three polarisation parameters (the\n                    <jats:italic>x<\/jats:italic>\n                    \u2010\n                    <jats:italic>y<\/jats:italic>\n                    linear diattenuation, the\n                    <jats:italic>x<\/jats:italic>\n                    \u2010\n                    <jats:italic>y<\/jats:italic>\n                    linear depolarization and the \u00b145\u00b0 linear birefringence), with PSNR values of 33.4\u2009dB, 35.7\u2009dB and 40.0\u2009dB, respectively. From images of M\n                    <jats:sub>12<\/jats:sub>\n                    , M\n                    <jats:sub>22<\/jats:sub>\n                    and M\n                    <jats:sub>24<\/jats:sub>\n                    , the cell nuclei and intercellular stroma in the melanoma dermis can be identified with higher contrast. The values of these elements are specific: for the cell nuclei, M\n                    <jats:sub>22<\/jats:sub>\n                    ranges from \u22120.75 to \u22120.27 and M\n                    <jats:sub>12<\/jats:sub>\n                    ranges from \u22120.12 to \u22120.04; for the extracellular matrix, M\n                    <jats:sub>22<\/jats:sub>\n                    , M\n                    <jats:sub>12<\/jats:sub>\n                    and M\n                    <jats:sub>24<\/jats:sub>\n                    fall within \u22120.16 and \u22120.07, 0.06 and 0.16 and 0.09 and 0.57, respectively. Finally, a theoretical analysis is presented to explain the observations. The results obtained in this is helpful for clinic applications of Mueller matrix images where a method of interpreting measured Mueller matrices rapidly and accurately is essential.\n                  <\/jats:p>","DOI":"10.1111\/exd.70199","type":"journal-article","created":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T15:00:56Z","timestamp":1767452456000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Identifying Anisotropic Structures of Non\u2010Stained Melanoma Tissue From Images of Its Mueller Matrix Elements"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3696-7451","authenticated-orcid":false,"given":"Xiupin","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Medical Instrument, Innovation Center for Intelligent Ophthalmic Technologies and Equipment Shanghai University of Medicine &amp; Health Sciences  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyou","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Dermatology The First Affiliated Hospital of Army Medical University  Chongqing People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Medical Instrument, Innovation Center for Intelligent Ophthalmic Technologies and Equipment Shanghai University of Medicine &amp; Health Sciences  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Wu","sequence":"additional","affiliation":[{"name":"Chongqing Engineering Research Center of Pharmaceutical Sciences Chongqing Medical and Pharmaceutical College  Chongqing People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Medical Instrument, Innovation Center for Intelligent Ophthalmic Technologies and Equipment Shanghai University of Medicine &amp; Health Sciences  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanrong","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Optical Engineering Nanjing University of Science &amp; Technology  Nanjing Jiangsu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Optical Engineering Nanjing University of Science &amp; Technology  Nanjing Jiangsu People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Medical Instrument, Innovation Center for Intelligent Ophthalmic Technologies and Equipment Shanghai University of Medicine &amp; Health Sciences  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanqing","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Medical Instrument, Innovation Center for Intelligent Ophthalmic Technologies and Equipment Shanghai University of Medicine &amp; Health Sciences  Shanghai People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,3]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1364\/OL.39.006050"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1364\/JOSAB.36.000F72"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-14804-z"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.5.004223"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.21.7.071112"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.20.5.056012"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/03772063.2017.1323562"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.20.10.105009"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.1486248"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3103\/S1060992X1102010X"},{"key":"e_1_2_10_12_1","first-page":"422","volume-title":"In Sixth International Conference on Correlation Optics","author":"Ushenko A. 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