{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T08:19:31Z","timestamp":1782893971620,"version":"3.54.5"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,5,5]],"date-time":"2016-05-05T00:00:00Z","timestamp":1462406400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Fundamemntal Clinical Pharma"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hypertension is highly prevalent; in Mexico, the 2012 National Health and Nutrition Survey reported a prevalence of hypertension of 31.5% in the adult population. Pharmacological treatment is the commonest intervention and has been shown to reduce cardiovascular mortality and morbidity, and total mortality. Accordingly, the type and number of antihypertensives used and the outcome \u2014 in terms of blood pressure (<jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>) control \u2014 are important. Therefore, our purpose is to learn the pattern of antihypertensive drug prescription and explore the determinants of <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> control in an urban population in Mexico. A retrospective cross\u2010sectional drug utilization study was conducted. Medical records from a community health centre were searched to identify those corresponding to patients diagnosed with hypertension; information upon antihypertensives used and control of the disease was carefully retrieved. A logistic regression model was built to know the main determinants of <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> control. A sample of 345 clinical records of interest was identified. Most patients received antihypertensives (86.4%); the leading medications used were angiotensin\u2010converting enzyme inhibitors, 63.8%; beta\u2010blockers (26.5%), diuretics (19.8%), angiotensin\u2010receptor blockers (15.8%) and calcium\u2010channel blockers (6.4%). Only the age (\u226555 years) and <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> (&gt;30) of the patients, and the age of the doctors (\u226555 years), had an important influence on <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> control. Obesity is a particular and important determinant of uncontrolled hypertension; it is worth to act on body weight, on an individual basis. As lack of control has been also tied to elderly doctors, an education programme could be envisaged.<\/jats:p>","DOI":"10.1111\/fcp.12179","type":"journal-article","created":{"date-parts":[[2016,1,20]],"date-time":"2016-01-20T02:03:05Z","timestamp":1453255385000},"page":"276-281","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prescription patterns of antihypertensives in a community health centre in Mexico City: a drug utilization study"],"prefix":"10.1111","volume":"30","author":[{"given":"Adela","family":"Alba\u2010Leonel","sequence":"first","affiliation":[{"name":"Nursing Obstetric National School and Department of Public Health Autonomous National University of Mexico UNAM Mexico Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Carvajal","sequence":"additional","affiliation":[{"name":"Centro de Estudios sobre la Seguridad de los Medicamentos (CESME) Universidad de Valladolid Valladolid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4423-4493","authenticated-orcid":false,"given":"Immaculada","family":"Fierro","sequence":"additional","affiliation":[{"name":"Centro de Estudios sobre la Seguridad de los Medicamentos (CESME) Universidad de Valladolid Valladolid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Castillo\u2010N\u00e1jera","sequence":"additional","affiliation":[{"name":"Sanitary District Benito Juarez Public Health Services of the Federal District Mexico Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar","family":"Campos\u2010Ramos","sequence":"additional","affiliation":[{"name":"Sanitary District Benito Juarez Public Health Services of the Federal District Mexico Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Villa\u2010Romero","sequence":"additional","affiliation":[{"name":"Department of Public Health Faculty of Medicine Autonomous National University of Mexico (UNAM) Mexico Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Molina\u2010Guarneros","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Faculty of Medicine Autonomous National University of Mexico (UNAM) Mexico Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200311000-00002"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.7326\/M14-0773"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/fcp.12044"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)17741-1"},{"key":"e_1_2_6_6_1","unstructured":"Instituto Nacional de Salud P\u00fablica [INSP]. (2012).Encuesta Nacional de Salud y Nutrici\u00f3n (ENSANUT) 2012.http:\/\/ensanut.insp.mx\/informes\/ENSANUT2012.ResultadosNacionales.pdf Accesed July 17th 2015."},{"issue":"2","key":"e_1_2_6_7_1","doi-asserted-by":"crossref","first-page":"S144","DOI":"10.21149\/spm.v55s2.5110","article-title":"Hypertension: prevalence, early diagnosis, control and trends in Mexican adults","volume":"55","author":"Campos\u2010Nonato I.","year":"2013","journal-title":"Salud Publica Mex."},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-36342001000500005"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200401000-00003"},{"issue":"1","key":"e_1_2_6_10_1","first-page":"S63","article-title":"Hypertension in Mexican adults: results from the National Health and Nutrition Survey 2006","volume":"52","author":"Barquera S.","year":"2010","journal-title":"Salud Publica Mex."},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000107251.49515.c2"},{"key":"e_1_2_6_12_1","first-page":"17","article-title":"Pattern and costs of the antihypertensive treatment for ambulatory patients in a general hospital (In Spanish)","volume":"21","author":"Ju\u00e1rez\u2010Garc\u00eda M.","year":"2008","journal-title":"Rev Soc Peru Med Interna"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-007-0266-8"},{"key":"e_1_2_6_14_1","first-page":"273","article-title":"Anti\u2010hypertensive drug utilization in Continental Portugal (1999\u20102004)","volume":"25","author":"Furtado C.","year":"2006","journal-title":"Portugal Rev Port Cardiol"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.5414\/CPP48068"},{"key":"e_1_2_6_16_1","first-page":"43","article-title":"Drug prescribing for hypertension at primary healthcare facilities in Trinidad","volume":"61","author":"Clement Y.N.","year":"2012","journal-title":"West Indian Med. 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