{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:40:58Z","timestamp":1792633258900,"version":"4.5.0"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,24]],"date-time":"2016-11-24T00:00:00Z","timestamp":1479945600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"},{"start":{"date-parts":[[2016,11,24]],"date-time":"2016-11-24T00:00:00Z","timestamp":1479945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fundam Clin Pharmacol"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1111\/fcp.12247","type":"journal-article","created":{"date-parts":[[2016,10,14]],"date-time":"2016-10-14T02:33:52Z","timestamp":1476412432000},"page":"237-244","source":"Crossref","is-referenced-by-count":13,"title":["Drug-induced progressive multifocal leukoencephalopathy: a case\/noncase study in the French pharmacovigilance database"],"prefix":"10.1111","volume":"31","author":[{"given":"Olivier","family":"Colin","sequence":"first","affiliation":[{"name":"Service de Pharmacologie Clinique et Vigilances; CHU de Poitiers; 2 rue de la mil\u00e9trie 86021 Poitiers France"},{"name":"Service de Neurologie; CHU de Poitiers; 2 rue de la mil\u00e9trie 86021 Poitiers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Favreli\u00e8re","sequence":"additional","affiliation":[{"name":"Service de Pharmacologie Clinique et Vigilances; CHU de Poitiers; 2 rue de la mil\u00e9trie 86021 Poitiers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Quillet","sequence":"additional","affiliation":[{"name":"Service de Pharmacologie Clinique et Vigilances; CHU de Poitiers; 2 rue de la mil\u00e9trie 86021 Poitiers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Philippe","family":"Neau","sequence":"additional","affiliation":[{"name":"Service de Neurologie; CHU de Poitiers; 2 rue de la mil\u00e9trie 86021 Poitiers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Luc","family":"Houeto","sequence":"additional","affiliation":[{"name":"Service de Neurologie; CHU de Poitiers; 2 rue de la mil\u00e9trie 86021 Poitiers France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Lafay-Chebassier","sequence":"additional","affiliation":[{"name":"Service de Pharmacologie Clinique et Vigilances; CHU de Poitiers; 2 rue de la mil\u00e9trie 86021 Poitiers France"},{"name":"INSERM U1084 Experimental and Clinical Neurosciences Laboratory; University of Poitiers; Poitiers 1 rue Georges Bonnet, BP 633 TSA 51106 86073 POITIERS cedex9 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Christine","family":"P\u00e9rault-Pochat","sequence":"additional","affiliation":[{"name":"Service de Pharmacologie Clinique et Vigilances; CHU de Poitiers; 2 rue de la mil\u00e9trie 86021 Poitiers France"},{"name":"INSERM U1084 Experimental and Clinical Neurosciences Laboratory; University of Poitiers; Poitiers 1 rue Georges Bonnet, BP 633 TSA 51106 86073 POITIERS cedex9 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the French Pharmacovigilance Network","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,24]]},"reference":[{"key":"10.1111\/fcp.12247-BIB0001|fcp12247-cit-0001","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/00019052-200406000-00019","article-title":"New insights into progressive multifocal leukoencephalopathy","volume":"17","author":"Koralnik","year":"2004","journal-title":"Curr. Opin. Neurol."},{"key":"10.1111\/fcp.12247-BIB0002|fcp12247-cit-0002","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3949\/ccjm.78.s2.02","article-title":"History and current concepts in the pathogenesis of PML","volume":"78","author":"Major","year":"2011","journal-title":"Cleve. Clin. J. Med."},{"key":"10.1111\/fcp.12247-BIB0003|fcp12247-cit-0003","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1212\/WNL.0b013e31828c2fa1","article-title":"PML diagnostic criteria: consensus statement from the AAN Neuroinfectious Disease Section","volume":"80","author":"Berger","year":"2013","journal-title":"Neurology"},{"key":"10.1111\/fcp.12247-BIB0004|fcp12247-cit-0004","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1002\/ana.10827","article-title":"Changing incidence of central nervous system diseases in the EuroSIDA cohort","volume":"55","author":"D'Arminio Monforte","year":"2004","journal-title":"Ann. Neurol."},{"key":"10.1111\/fcp.12247-BIB0005|fcp12247-cit-0005","first-page":"117","article-title":"Stratification and monitoring of natalizumab-associated progressive multifocal leukoencephalopathy risk: recommendations from an expert group","volume":"87","author":"McGuigan","year":"2016","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1111\/fcp.12247-BIB0006|fcp12247-cit-0006","doi-asserted-by":"crossref","first-page":"969","DOI":"10.2165\/11537510-000000000-00000","article-title":"Progressive multifocal leukoencephalopathy and newer biological agents","volume":"33","author":"Berger","year":"2010","journal-title":"Drug Saf."},{"key":"10.1111\/fcp.12247-BIB0007|fcp12247-cit-0007","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/S1470-2045(09)70161-5","article-title":"Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a review from the Research on Adverse Drug Events and Reports (RADAR) project","volume":"10","author":"Carson","year":"2009","journal-title":"Lancet Oncol."},{"key":"10.1111\/fcp.12247-BIB0008|fcp12247-cit-0008","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1017\/S0317167100012105","article-title":"Monoclonal antibodies and progressive multifocal leukoencephalopathy","volume":"38","author":"Keene","year":"2011","journal-title":"Can. J. Neurol. Sci."},{"key":"10.1111\/fcp.12247-BIB0009|fcp12247-cit-0009","first-page":"507","article-title":"[Drug-induced dementia: a case\/non-case study in the French Pharmacovigilance database]","volume":"62","author":"Favreliere","year":"2007","journal-title":"Therapie"},{"key":"10.1111\/fcp.12247-BIB0010|fcp12247-cit-0010","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s00228-004-0813-5","article-title":"Upper gastrointestinal adverse drug reactions and cyclo-oxygenase-2 inhibitors (celecoxib and rofecoxib): a case\/non-case study from the French Pharmacovigilance Database","volume":"60","author":"Lugardon","year":"2004","journal-title":"Eur. J. Clin. Pharmacol."},{"key":"10.1111\/fcp.12247-BIB0011|fcp12247-cit-0011","first-page":"557","article-title":"[French pharmacovigilance database system: examples of utilisation]","volume":"50","author":"Moore","year":"1995","journal-title":"Therapie"},{"key":"10.1111\/fcp.12247-BIB0012|fcp12247-cit-0012","first-page":"301","volume-title":"Stephen's detection of new adverse drug reactions","author":"Ewans","year":"2004","edition":"5"},{"key":"10.1111\/fcp.12247-BIB0013|fcp12247-cit-0013","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1469-1809.1955.tb01348.x","article-title":"On estimating the relation between blood group and disease","volume":"19","author":"Woolf","year":"1955","journal-title":"Ann. Hum. Genet."},{"key":"10.1111\/fcp.12247-BIB0014|fcp12247-cit-0014","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1007\/s12016-012-8327-x","article-title":"Systemic lupus erythematosus, progressive multifocal leukoencephalopathy, and T-CD4? lymphopenia","volume":"43","author":"Brandao","year":"2012","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"10.1111\/fcp.12247-BIB0015|fcp12247-cit-0015","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1007\/s40263-015-0286-3","article-title":"Drug-induced progressive multifocal leukoencephalopathy: a comprehensive analysis of the WHO adverse drug reaction database","volume":"29","author":"Melis","year":"2015","journal-title":"CNS Drugs"},{"key":"10.1111\/fcp.12247-BIB0016|fcp12247-cit-0016","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1002\/pds.3414","article-title":"Disproportionality signal of progressive multifocal leukoencephalopathy: monoclonal antibodies versus other immunosuppressants","volume":"22","author":"Piccinni","year":"2013","journal-title":"Pharmacoepidemiol. Drug Saf."},{"key":"10.1111\/fcp.12247-BIB0017|fcp12247-cit-0017","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1002\/pds.3320","article-title":"Signals of progressive multifocal leukoencephalopathy for immunosuppressants: a disproportionality analysis of spontaneous reports within the US Adverse Event Reporting System (AERS)","volume":"21","author":"Schmedt","year":"2012","journal-title":"Pharmacoepidemiol. Drug Saf."},{"key":"10.1111\/fcp.12247-BIB0018|fcp12247-cit-0018","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1590\/0004-282X20130154","article-title":"Progressive multifocal leukoencephalopathy: new concepts","volume":"71","author":"Lima","year":"2013","journal-title":"Arq. Neuropsiquiatr."},{"key":"10.1111\/fcp.12247-BIB0019|fcp12247-cit-0019","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1177\/2042098612453849","article-title":"Treatment-related progressive multifocal leukoencephalopathy: current understanding and future steps","volume":"3","author":"Zaheer","year":"2012","journal-title":"Ther. Adv. Drug Saf."},{"key":"10.1111\/fcp.12247-BIB0020|fcp12247-cit-0020","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1002\/cpt.207","article-title":"Drug-induced progressive multifocal leukoencephalopathy: lessons learned from contrasting natalizumab and rituximab","volume":"98","author":"Vermeer","year":"2015","journal-title":"Clin. Pharmacol. Ther."},{"key":"10.1111\/fcp.12247-BIB0021|fcp12247-cit-0021","first-page":"25","article-title":"Long-term safety and efficacy of natalizumab in relapsing-remitting multiple sclerosis: impact on quality of life","volume":"5","author":"Planas","year":"2014","journal-title":"Patient Relat. Outcome Meas."},{"key":"10.1111\/fcp.12247-BIB0022|fcp12247-cit-0022","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1177\/0961203315622819","article-title":"Progressive multifocal leukoencephalopathy in patients with systemic lupus erythematosus: a systematic literature review","volume":"25","author":"Henegar","year":"2016","journal-title":"Lupus"},{"issue":"11 Suppl 8","key":"10.1111\/fcp.12247-BIB0023|fcp12247-cit-0023","first-page":"1","article-title":"Risk of biologic therapy-associated progressive multifocal leukoencephalopathy: use of the JC virus antibody assay in the treatment of moderate-to-severe Crohn's disease","volume":"8","author":"Lichtenstein","year":"2012","journal-title":"Gastroenterol. Hepatol."},{"key":"10.1111\/fcp.12247-BIB0024|fcp12247-cit-0024","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1056\/NEJMp048187","article-title":"Expecting the unexpected - drug safety, pharmacovigilance, and the prepared mind","volume":"351","author":"Trontell","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1111\/fcp.12247-BIB0025|fcp12247-cit-0025","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.clpt.2004.06.006","article-title":"Discovering adverse reactions: why does it take so long?","volume":"76","author":"Woosley","year":"2004","journal-title":"Clin. Pharmacol. Ther."},{"key":"10.1111\/fcp.12247-BIB0026|fcp12247-cit-0026","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1056\/NEJMc1506151","article-title":"PML in patients treated with dimethyl fumarate","volume":"373","author":"Balak","year":"2015","journal-title":"N. Engl. J. Med."},{"key":"10.1111\/fcp.12247-BIB0027|fcp12247-cit-0027","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1212\/WNL.0000000000002654","article-title":"Fingolimod-associated PML in a patient with prior immunosuppression","volume":"86","author":"Gyang","year":"2016","journal-title":"Neurology"},{"key":"10.1111\/fcp.12247-BIB0028|fcp12247-cit-0028","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1111\/fcp.12214","article-title":"Overview of drug data within French health insurance databases and implications for pharmacoepidemiological studies","volume":"30","author":"Palmaro","year":"2016","journal-title":"Fundam. Clin. Pharmacol."},{"key":"10.1111\/fcp.12247-BIB0029|fcp12247-cit-0029","first-page":"111","article-title":"Lagier G [Imputation of the unexpected or toxic effects of drugs. Actualization of the method used in France]","volume":"40","author":"Begaud","year":"1985","journal-title":"Therapie"},{"key":"10.1111\/fcp.12247-BIB0030|fcp12247-cit-0030","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1111\/j.1365-2125.2011.04087.x","article-title":"When to publish measures of disproportionality derived from spontaneous reporting databases?","volume":"72","author":"Boer","year":"2011","journal-title":"Br. J. Clin. Pharmacol."}],"container-title":["Fundamental & Clinical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ffcp.12247","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/fcp.12247\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T09:44:12Z","timestamp":1625391852000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/fcp.12247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,24]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,4]]}},"URL":"https:\/\/doi.org\/10.1111\/fcp.12247","archive":["Portico"],"relation":{},"ISSN":["0767-3981"],"issn-type":[{"value":"0767-3981","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11,24]]}}}