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Therefore, an effort has been made in the present review to discuss the role of double\u2010stranded RNA\u2010dependent protein kinase and above\u2010mentioned mechanisms in the progression of Met S, along with its interlinking in major clinical manifestations of Met S such as hypertension and diabetic cardiomyopathy.<\/jats:p>","DOI":"10.1111\/fcp.12261","type":"journal-article","created":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T22:06:40Z","timestamp":1482185200000},"page":"265-279","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Double\u2010stranded RNA\u2010dependent protein kinase signalling and paradigms of cardiometabolic syndrome"],"prefix":"10.1111","volume":"31","author":[{"given":"Jaspreet","family":"Kalra","sequence":"first","affiliation":[{"name":"Department of Pharmacy Birla Institute of Technology and Sciences Pilani, Hyderabad Campus Jawahar Nagar Shameerpet, Hyderabad Andhra Pradesh 500078 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arti","family":"Dhar","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Birla Institute of Technology and Sciences Pilani, Hyderabad Campus Jawahar Nagar Shameerpet, Hyderabad Andhra Pradesh 500078 India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.2174\/1573403X12666160526122600"},{"key":"e_1_2_11_3_1","unstructured":"www.idf.org\/metabolicsyndrome website of the International Diabetes Federation(accessed on 23 June 2016)."},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612811319270002"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/943162"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms140510497"},{"key":"e_1_2_11_7_1","first-page":"174","article-title":"Obesity\u2010associated low\u2010grade inflammation in type 2 diabetes mellitus: causes and consequences","volume":"71","author":"Van Greevenbroek M.M.","year":"2013","journal-title":"Neth. 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