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The basic academic knowledge of general medicine students, who have often not yet encountered clinical situations of dyskalemia, remains unclear in this regard.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The purpose of this study was to evaluate the knowledge and reflexive practices of general medicine students in regard to dyskalemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional survey, based on a self\u2010questionnaire, of all of the students enrolled in general medicine studies at the Faculty of Medicine at the University of Nancy (France) at the end of their degree. The students were asked questions pertaining to specific clinical situations. The answers were compared to the information provided in the medical curriculum as well as to the relevant European guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We collected 290 of the questionnaires (participation rate: 81.2%). The hyper\u2010 and hypokalemia thresholds considered pathological (3.5\u20135.0\u00a0mmol\/L) were known by 78% and 67% of the students, respectively. The perception of danger in case of severe hypokalemia was underestimated by 62.7% of them. In most cases, the proposed management of hyperkalemia in heart and renal failure did not comply with the relevant guidelines. The students tended to favor permanent discontinuation of the administration of converting enzyme inhibitors (ACE) and\/or mineralocorticoid receptor antagonists (MRA) without considering the need for their reintroduction (51.6%). Sodium polystyrene sulfate was frequently seen as an appropriate first\u2010line treatment for hyperkalemia (45%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The knowledge and competence of general medicine students appear to be lacking for hyperkalemia in heart and renal failure, and they are long way from full compliance with the relevant European guidelines. Exposure to complex clinical situations as part of the medical curriculum, therefore, seems essential to improve the way dyskalemia is managed in France.<\/jats:p><\/jats:sec>","DOI":"10.1111\/fcp.12621","type":"journal-article","created":{"date-parts":[[2020,10,24]],"date-time":"2020-10-24T18:07:33Z","timestamp":1603562853000},"page":"473-484","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Dyskalemia: a management problem for students"],"prefix":"10.1111","volume":"35","author":[{"given":"Lisa","family":"Senninger","sequence":"first","affiliation":[{"name":"Universit\u00e9 de Lorraine Nancy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laure","family":"Abensur Vuillaume","sequence":"additional","affiliation":[{"name":"Inserm Centre d\u2019Investigations Cliniques\u2010 Plurith\u00e9matique 14\u201033, and Inserm U1116, CHRU F\u2010CRIN INI\u2010CRCT (Cardiovascular and Renal Clinical Trialists) Universit\u00e9 de Lorraine Vandoeuvre France"},{"name":"Emergency Departement Regional Hospital Metz Thionville France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luc","family":"Frimat","sequence":"additional","affiliation":[{"name":"Inserm Centre d\u2019Investigations Cliniques\u2010 Plurith\u00e9matique 14\u201033, and Inserm U1116, CHRU F\u2010CRIN INI\u2010CRCT (Cardiovascular and Renal Clinical Trialists) Universit\u00e9 de Lorraine Vandoeuvre France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Girerd","sequence":"additional","affiliation":[{"name":"Inserm Centre d\u2019Investigations Cliniques\u2010 Plurith\u00e9matique 14\u201033, and Inserm U1116, CHRU F\u2010CRIN INI\u2010CRCT (Cardiovascular and Renal Clinical Trialists) Universit\u00e9 de Lorraine Vandoeuvre France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zohra","family":"Lamiral","sequence":"additional","affiliation":[{"name":"Inserm Centre d\u2019Investigations Cliniques\u2010 Plurith\u00e9matique 14\u201033, and Inserm U1116, CHRU F\u2010CRIN INI\u2010CRCT (Cardiovascular and Renal Clinical Trialists) Universit\u00e9 de Lorraine Vandoeuvre France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Rossignol","sequence":"additional","affiliation":[{"name":"Inserm Centre d\u2019Investigations Cliniques\u2010 Plurith\u00e9matique 14\u201033, and Inserm U1116, CHRU F\u2010CRIN INI\u2010CRCT (Cardiovascular and Renal Clinical Trialists) Universit\u00e9 de Lorraine Vandoeuvre France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7683-0022","authenticated-orcid":false,"given":"Jean\u2010Marc","family":"Boivin","sequence":"additional","affiliation":[{"name":"Inserm Centre d\u2019Investigations Cliniques\u2010 Plurith\u00e9matique 14\u201033, and Inserm U1116, CHRU F\u2010CRIN INI\u2010CRCT (Cardiovascular and Renal Clinical Trialists) Universit\u00e9 de Lorraine Vandoeuvre France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,12,3]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"104","article-title":"Short\u2010term mortality risk of serum potassium levels in hypertension: a retrospective analysis of nationwide registry data","volume":"38","author":"Krogager M.L.","year":"2017","journal-title":"Eur. 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