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The objective of this study is to determine the prescription patterns and approved and unapproved indications for tetracyclines in a group of patients in Colombia. This was a cross\u2010sectional study, based on a database of medication dispensing of approximately 8.5 million people affiliated with the Colombian Health System, of the indications for the use of tetracyclines in outpatients. Sociodemographic, pharmacological, and comorbidity variables were considered. A total of 20\u2009699 patients with a prescription of tetracyclines were identified, with a median age of 26.1\u00a0years; 65.0% were women. The most prescribed tetracycline was doxycycline (95.1%), especially for the treatment of acne (55.3%). A total of 23.5% of the prescriptions was used for unapproved indications, for example, vaginitis\u2010vulvitis\u2010vulvovaginitis (8.1%). Increasing age, prescriptions of doxycycline made by general physician, and woman attended by general physician were associated with a greater probability that a tetracycline was used for unapproved indications. Residing in Bogota\u2010Cundinamarca Region and woman that residing in Bogota\u2010Cundinamarca reduced this risk. A high proportion of patients received tetracyclines for dermatological conditions, with a lower proportion of use for gynecological and respiratory infections. For approximately one quarter of the cases, tetracyclines were prescribed for indications not approved by regulatory agencies, especially in those over 18\u2009years and when the prescriptions of doxycycline was made by a general practitioners.<\/jats:p>","DOI":"10.1111\/fcp.12724","type":"journal-article","created":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T18:13:30Z","timestamp":1630779210000},"page":"390-396","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Study of prescription\u2010indication of tetracyclines in a population in Colombia"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4245-0101","authenticated-orcid":false,"given":"Luis Fernando","family":"Valladales\u2010Restrepo","sequence":"first","affiliation":[{"name":"Grupo de Investigaci\u00f3n en Farmacoepidemiolog\u00eda y Farmacovigilancia Universidad Tecnol\u00f3gica de Pereira\u2010Audifarma S. A.  Pereira Risaralda Colombia"},{"name":"Grupo de Investigaci\u00f3n Biomedicina, Facultad de Medicina Fundaci\u00f3n Universitaria Aut\u00f3noma de las Am\u00e9ricas  Pereira Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camilo Alexander","family":"Constain\u2010Mosquera","sequence":"additional","affiliation":[{"name":"Semillero de Investigaci\u00f3n en Farmacolog\u00eda Geri\u00e1trica, Grupo de Investigaci\u00f3n Biomedicina, Facultad de Medicina Fundaci\u00f3n Universitaria Aut\u00f3noma de las Am\u00e9ricas  Pereira Risaralda Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"\u00c1lvarez\u2010Amaya","sequence":"additional","affiliation":[{"name":"Semillero de Investigaci\u00f3n en Farmacolog\u00eda Geri\u00e1trica, Grupo de Investigaci\u00f3n Biomedicina, Facultad de Medicina Fundaci\u00f3n Universitaria Aut\u00f3noma de las Am\u00e9ricas  Pereira Risaralda Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8455-0936","authenticated-orcid":false,"given":"Jorge Enrique","family":"Machado\u2010Alba","sequence":"additional","affiliation":[{"name":"Grupo de Investigaci\u00f3n en Farmacoepidemiolog\u00eda y Farmacovigilancia Universidad Tecnol\u00f3gica de Pereira\u2010Audifarma S. 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