{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T00:11:35Z","timestamp":1790381495374,"version":"4.1.0"},"reference-count":55,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,6,20]],"date-time":"2013-06-20T00:00:00Z","timestamp":1371686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genes Brain and Behavior"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:p><jats:bold>Candidate genes have been identified for both reading and language, but most of the heritable variance in these traits remains unexplained. Here, we report a genome\u2010wide association meta\u2010analysis of two large cohorts: population samples of Australian twins and siblings aged 12\u201325\u2009years (<jats:italic>n<\/jats:italic>\u2009=\u20091177 from 538 families), and a younger cohort of children of the <jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content> Avon Longitudinal Study of Parents and their Children (aged 8 and 9\u2009years; maximum <jats:italic>n<\/jats:italic>\u2009=\u20095472). Suggestive association was indicated for reading measures and non\u2010word repetition (<jats:styled-content style=\"fixed-case\">NWR<\/jats:styled-content>), with the greatest support found for single nucleotide polymorphisms (<jats:styled-content style=\"fixed-case\">SNPs<\/jats:styled-content>) in the pseudogene, <jats:italic><jats:styled-content style=\"fixed-case\">ABCC13<\/jats:styled-content><\/jats:italic> (<jats:italic>P<\/jats:italic>\u2009=\u20097.34\u2009\u00d7\u200910<jats:sup>\u22128<\/jats:sup>), and the gene, <jats:italic><jats:styled-content style=\"fixed-case\">DAZAP1<\/jats:styled-content><\/jats:italic> (<jats:italic>P<\/jats:italic>\u2009=\u20091.32\u2009\u00d7\u200910<jats:sup>\u22126<\/jats:sup>). Gene\u2010based analyses showed significant association (<jats:italic>P<\/jats:italic>\u2009&lt;\u20092.8\u2009\u00d7\u200910<jats:sup>\u22126<\/jats:sup>) for reading and spelling with genes <jats:italic><jats:styled-content style=\"fixed-case\">CD2L1<\/jats:styled-content><\/jats:italic>, <jats:italic><jats:styled-content style=\"fixed-case\">CDC2L2<\/jats:styled-content><\/jats:italic> and <jats:italic><jats:styled-content style=\"fixed-case\">RCAN3<\/jats:styled-content><\/jats:italic> in two loci on chromosome 1. Some support was found for the same <jats:styled-content style=\"fixed-case\">SNPs<\/jats:styled-content> having effects on both reading skill and <jats:styled-content style=\"fixed-case\">NWR<\/jats:styled-content>, which is compatible with behavior genetic evidence for influences of reading acquisition on phonological\u2010task performance. The results implicate novel candidates for study in additional cohorts for reading and language abilities.<\/jats:bold><\/jats:p>","DOI":"10.1111\/gbb.12053","type":"journal-article","created":{"date-parts":[[2013,6,6]],"date-time":"2013-06-06T00:12:42Z","timestamp":1370477562000},"page":"645-652","source":"Crossref","is-referenced-by-count":109,"title":["A genome\u2010wide association study for reading and language abilities in two population cohorts"],"prefix":"10.1111","volume":"12","author":[{"given":"M.","family":"Luciano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. M.","family":"Evans","sequence":"additional","affiliation":[{"name":"MRC Centre for Causal Analyses in Translational Epidemiology School of Social and Community Medicine, University of Bristol Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. 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