{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:49:05Z","timestamp":1791330545262,"version":"4.3.1"},"reference-count":42,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,6,16]],"date-time":"2014-06-16T00:00:00Z","timestamp":1402876800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"U.S. National Institutes of Health (NIH)","award":["NS031348"],"award-info":[{"award-number":["NS031348"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genes Brain and Behavior"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>\n                    Twenty\u2010seven inbred strains of mice were tested for spike\u2010wave discharge (SWD) activity by video\u2010electroencephalographic recordings over a 24\u2010h recording period. Eight strains had reproducible, frequent SWDs, including five strains (\n                    <jats:styled-content style=\"fixed-case\">C57BLKS<\/jats:styled-content>\n                    \/J,\n                    <jats:styled-content style=\"fixed-case\">CBA<\/jats:styled-content>\n                    \/J,\n                    <jats:styled-content style=\"fixed-case\">DBA<\/jats:styled-content>\n                    \/\n                    <jats:styled-content style=\"fixed-case\">1J<\/jats:styled-content>\n                    ,\n                    <jats:styled-content style=\"fixed-case\">NOR<\/jats:styled-content>\n                    \/\n                    <jats:styled-content style=\"fixed-case\">LtJ<\/jats:styled-content>\n                    ,\n                    <jats:styled-content style=\"fixed-case\">SM<\/jats:styled-content>\n                    \/J) previously undiagnosed for this distinctive phenotype. Eighteen other strains exhibited no such activity. Spike\u2010wave discharges usually occurred while the subject was motionless, and in a significant number of annotated instances coincided with an arrest of the subject's relatively unrestrained locomotor activity, which resumed immediately after the discharge ended. In all five new strains, SWDs were suppressed by ethosuximide administration. From the genealogy of inbred strains, we suggest that two ancestors, A and\n                    <jats:styled-content style=\"fixed-case\">DBA<\/jats:styled-content>\n                    , transmitted genotypes required for SWD in all positive strains. Together these strains with SWDs provide new opportunities to understand the genetic core susceptibility of this distinctive electroencephalographic activity and to explore its relationship to absence epilepsy, a human disorder for which few genes are known.\n                  <\/jats:p>","DOI":"10.1111\/gbb.12142","type":"journal-article","created":{"date-parts":[[2014,5,24]],"date-time":"2014-05-24T06:43:06Z","timestamp":1400913786000},"page":"519-526","source":"Crossref","is-referenced-by-count":44,"title":["Hidden in plain sight: spike\u2010wave discharges in mouse inbred strains"],"prefix":"10.1111","volume":"13","author":[{"given":"V. A.","family":"Letts","sequence":"first","affiliation":[{"name":"The Jackson Laboratory  Bar Harbor ME USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. 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