{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T22:56:33Z","timestamp":1772751393890,"version":"3.50.1"},"reference-count":70,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,5,23]],"date-time":"2017-05-23T00:00:00Z","timestamp":1495497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"AISC (Associazione Italiana Sindrome di Costello)"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genes Brain and Behavior"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:p>Ventral and dorsal streams are visual pathways deputed to transmit information from the photoreceptors of the retina to the lateral geniculate nucleus and then to the primary visual cortex (<jats:styled-content style=\"fixed-case\">V1<\/jats:styled-content>). Several studies investigated whether one pathway is more vulnerable than the other during development, and whether these streams develop at different rates. The results are still discordant. The aim of the present study was to understand the functionality of the dorsal and the ventral streams in two populations affected by different genetic disorders, Noonan syndrome (<jats:styled-content style=\"fixed-case\">NS<\/jats:styled-content>) and 22q11.2 deletion syndrome (22q11.<jats:styled-content style=\"fixed-case\">2DS<\/jats:styled-content>), and explore the possible genotype\u2013phenotype relationships. \u2018Form coherence\u2019 abilities for the ventral stream and \u2018motion coherence\u2019 abilities for the dorsal stream were evaluated in 19 participants with <jats:styled-content style=\"fixed-case\">NS<\/jats:styled-content> and 20 participants with 22q11.<jats:styled-content style=\"fixed-case\">2DS<\/jats:styled-content>. Collected data were compared with 55 age\u2010matched controls. Participants with <jats:styled-content style=\"fixed-case\">NS<\/jats:styled-content> and 22q11.<jats:styled-content style=\"fixed-case\">2DS<\/jats:styled-content> did not differ in the form coherence task, and their performance was significantly lower than that of controls. However, in the motion coherence task, the group with <jats:styled-content style=\"fixed-case\">NS<\/jats:styled-content> and controls did not differ, and both obtained significantly higher scores than the group with 22q11.<jats:styled-content style=\"fixed-case\">2DS<\/jats:styled-content>. Our findings indicate that deficits in the dorsal stream are related to the specific genotype, and that in our syndromic groups the ventral stream is more vulnerable than the dorsal stream.<\/jats:p>","DOI":"10.1111\/gbb.12381","type":"journal-article","created":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T18:22:42Z","timestamp":1491416562000},"page":"627-634","source":"Crossref","is-referenced-by-count":4,"title":["Visual perception skills: a comparison between patients with <scp>N<\/scp>oonan syndrome and 22q11.2 deletion syndrome"],"prefix":"10.1111","volume":"16","author":[{"given":"G.","family":"Piccini","sequence":"first","affiliation":[{"name":"Department of Neuroscience, Child Neuropsychiatric Unit Bambino Ges\u00f9 Children's Hospital, IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Menghini","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Child Neuropsychiatric Unit Bambino Ges\u00f9 Children's Hospital, IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"D'Andrea","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Imaging and Clinical Sciences, Institute for Advanced Biomedical Technologies University \u201cG.d'Annunzio\u201d  Chieti\u2010Pescara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Caciolo","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Child Neuropsychiatric Unit Bambino Ges\u00f9 Children's Hospital, IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Pontillo","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Child Neuropsychiatric Unit Bambino Ges\u00f9 Children's Hospital, IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Armando","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Child Neuropsychiatric Unit Bambino Ges\u00f9 Children's Hospital, IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Perrino","sequence":"additional","affiliation":[{"name":"Center for Rare Diseases, Department of Pediatrics, Polo Salute Donna e Bambino Fondazione Policlinico Universitario A. Gemelli, Catholic University  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Mandolesi","sequence":"additional","affiliation":[{"name":"Psychology Department University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Salerni","sequence":"additional","affiliation":[{"name":"Institute of Ophthalmology Catholic University  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Buzzonetti","sequence":"additional","affiliation":[{"name":"Ophthalmology Department Bambino Ges\u00f9 Children's Hospital, IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. C.","family":"Digilio","sequence":"additional","affiliation":[{"name":"Genetics and Rare Diseases Research Division Bambino Ges\u00f9 Children's Hospital, IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Zampino","sequence":"additional","affiliation":[{"name":"Center for Rare Diseases, Department of Pediatrics, Polo Salute Donna e Bambino Fondazione Policlinico Universitario A. Gemelli, Catholic University  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Tartaglia","sequence":"additional","affiliation":[{"name":"Genetics and Rare Diseases Research Division Bambino Ges\u00f9 Children's Hospital, IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Benassi","sequence":"additional","affiliation":[{"name":"Psychology Department University of Bologna  Bologna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Vicari","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Child Neuropsychiatric Unit Bambino Ges\u00f9 Children's Hospital, IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2197-9417","authenticated-orcid":false,"given":"P.","family":"Alfieri","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Child Neuropsychiatric Unit Bambino Ges\u00f9 Children's Hospital, IRCCS  Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,23]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1216354"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.34229"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(07)64007-2"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952523813000497"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199705260-00025"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1076\/jcen.23.4.447.1228"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhl097"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhn064"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952523898153117"},{"key":"e_1_2_5_11_1","unstructured":"Beery K.E.&Buktenica N.A.(2000)The Beery\u2013Buktenica Developmental Test of Visual\u2013Motor Integration. NCS Pearson Minneapolis MN (Italian translation by C. Preda). O.S. organizzazioni speciali Florence."},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNR.0b013e3282f228c8"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.wnr.0000129855.50780.85"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.visres.2011.02.018"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(00)00540-6"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3932(03)00178-7"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.visres.2005.07.021"},{"key":"e_1_2_5_18_1","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1523\/JNEUROSCI.13-05-01916.1993","article-title":"Development of local circuits in human visual cortex","volume":"13","author":"Burkhalter A.","year":"1993","journal-title":"J Neurosci"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1167\/12.7.11"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awl066"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhl142"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-007-0582-0"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617703930098"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511544101.010"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.157.3.409"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00125817-200101000-00011"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.03.044"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1167\/14.10.804"},{"key":"e_1_2_5_29_1","first-page":"853","article-title":"A test for the evaluation of form perception ability: form coherence test","volume":"42","author":"Giovagnoli S.","year":"2015","journal-title":"Giorn It Psicol"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320450307"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2004.03.002"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1002171011644"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200105250-00045"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/00019605-200310000-00013"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2012.03.023"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/26.8.503"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2006.03.011"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2013.09.013"},{"key":"e_1_2_5_39_1","first-page":"481","volume-title":"The Visual Neuroscience","author":"Kaplan E.","year":"2004"},{"key":"e_1_2_5_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(00)01002-7"},{"key":"e_1_2_5_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-013-9232-5"},{"key":"e_1_2_5_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61601-8"},{"key":"e_1_2_5_43_1","doi-asserted-by":"publisher","DOI":"10.1080\/09297040590911202"},{"key":"e_1_2_5_44_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.07-11-03416.1987"},{"key":"e_1_2_5_45_1","doi-asserted-by":"publisher","DOI":"10.1186\/s11689-016-9135-z"},{"key":"e_1_2_5_46_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952523899156177"},{"key":"e_1_2_5_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2011.06.012"},{"key":"e_1_2_5_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2009.11.003"},{"key":"e_1_2_5_49_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ne.16.030193.002101"},{"key":"e_1_2_5_50_1","volume-title":"The Visual Brain in Action","author":"Milner A.D.","year":"1995"},{"key":"e_1_2_5_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(83)90190-X"},{"key":"e_1_2_5_52_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.08-06-02201.1988"},{"key":"e_1_2_5_53_1","doi-asserted-by":"publisher","DOI":"10.1177\/000992289403300907"},{"key":"e_1_2_5_54_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200208070-00010"},{"key":"e_1_2_5_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.visres.2004.10.005"},{"key":"e_1_2_5_56_1","volume-title":"CPM, Coloured Progressive Matrices","author":"Raven J.C.","year":"1996"},{"key":"e_1_2_5_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(00)00524-8"},{"key":"e_1_2_5_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3932(97)00004-3"},{"key":"e_1_2_5_59_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.2000.00194.x"},{"key":"e_1_2_5_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2004.11.006"},{"key":"e_1_2_5_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2014.10.025"},{"key":"e_1_2_5_62_1","first-page":"1","article-title":"Dorsal and ventral visual streams: typical and atypical development","volume":"9","author":"Simic N.","year":"2016","journal-title":"Child Neuropsychol"},{"key":"e_1_2_5_63_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200008210-00031"},{"key":"e_1_2_5_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.21206"},{"key":"e_1_2_5_65_1","doi-asserted-by":"publisher","DOI":"10.1076\/0929-7049(199912)05:04;1-R;FT230"},{"key":"e_1_2_5_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2010.05790.x"},{"key":"e_1_2_5_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2016.06.061"},{"key":"e_1_2_5_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10519-011-9499-5"},{"key":"e_1_2_5_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6989(91)90119-P"},{"key":"e_1_2_5_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2009.12.020"},{"key":"e_1_2_5_71_1","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.30.10.852"}],"container-title":["Genes, Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fgbb.12381","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/gbb.12381","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T18:17:54Z","timestamp":1696357074000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/gbb.12381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,23]]},"references-count":70,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1111\/gbb.12381"],"URL":"https:\/\/doi.org\/10.1111\/gbb.12381","archive":["Portico"],"relation":{},"ISSN":["1601-1848","1601-183X"],"issn-type":[{"value":"1601-1848","type":"print"},{"value":"1601-183X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,23]]}}}