{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T15:57:24Z","timestamp":1782489444102,"version":"3.54.5"},"reference-count":152,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["STPGP\u2010521253\u20102018"],"award-info":[{"award-number":["STPGP\u2010521253\u20102018"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Genes Brain and Behavior"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Aquaculturists use polyploid fish to maximize production albeit with some unintended consequences including compromised behaviors and physiological function. Given benefits of probiotic therapies (e.g., improved immune response, growth, and metabolism), we explored probiotic supplementation (mixture of <jats:italic>Bifidobacterium<\/jats:italic>, <jats:italic>Lactobacillus<\/jats:italic>, and <jats:italic>Lactococcus<\/jats:italic>), to overcome drawbacks. We first examined fish gut bacterial community composition using 16S metabarcoding (via principal coordinate analyses and PERMANOVA) and determined probiotics significantly impacted gut bacteria composition (<jats:italic>p<\/jats:italic>\u2009=\u20090.001). Secondly, we examined how a genomic disruptor (triploidy) and diet supplements (probiotics) impact gene transcription and behavioral profiles of hatchery\u2010reared Chinook salmon (<jats:italic>Oncorhynchus tshawytscha<\/jats:italic>). Juveniles from four treatment groups (diploid\u2010regular feed, diploid\u2010probiotic feed, triploid\u2010regular feed, and triploid\u2010probiotic feed; <jats:italic>n<\/jats:italic>\u2009=\u2009360) underwent behavioral assays to test activity, exploration, neophobia, predator evasion, aggression\/sociality, behavioral sensitivity, and flexibility. In these fish, transcriptional profiles for genes associated with neural functions (neurogenesis\/synaptic plasticity) and biomarkers for stress response and development (growth\/appetite) were (i) examined across treatments and (ii) used to describe behavioral phenotypes via principal component analyses and general linear mixed models. Triploids exhibited a more active behavioral profile (<jats:italic>p<\/jats:italic>\u2009=\u20090.002), and those on a regular diet had greater Neuropeptide Y transcription (<jats:italic>p<\/jats:italic>\u2009=\u20090.02). A growth gene (early growth response protein 1, <jats:italic>p<\/jats:italic>\u2009=\u20090.02) and long\u2010term neural development genes (neurogenic differentiation factor, <jats:italic>p<\/jats:italic>\u2009=\u20090.003 and synaptysomal\u2010associated protein 25\u2010a, <jats:italic>p<\/jats:italic>\u2009=\u20090.005) impacted activity and reactionary profiles, respectively. Overall, our probiotic treatment did not compensate for triploidy. Our research highlights novel applications of behavioral transcriptomics for identifying candidate genes and dynamic, mechanistic associations with complex behavioral repertoires.<\/jats:p>","DOI":"10.1111\/gbb.12898","type":"journal-article","created":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T06:41:22Z","timestamp":1717137682000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Behavioral transcriptomic effects of triploidy and probiotic therapy (<i>Bifidobacterium<\/i>, <i>Lactobacillus<\/i>, and <i>Lactococcus<\/i> mixture) on juvenile Chinook salmon (<i>Oncorhynchus tshawytscha<\/i>)"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-1907-3501","authenticated-orcid":false,"given":"Chelsea E.","family":"Frank","sequence":"first","affiliation":[{"name":"Department of Integrative Biology University of Windsor  Windsor Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javad","family":"Sadeghi","sequence":"additional","affiliation":[{"name":"Great Lakes Institute for Environmental Research University of Windsor  Windsor Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel D.","family":"Heath","sequence":"additional","affiliation":[{"name":"Department of Integrative Biology University of Windsor  Windsor Ontario Canada"},{"name":"Great Lakes Institute for Environmental Research University of Windsor  Windsor Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina A. D.","family":"Semeniuk","sequence":"additional","affiliation":[{"name":"Department of Integrative Biology University of Windsor  Windsor Ontario Canada"},{"name":"Great Lakes Institute for Environmental Research University of Windsor  Windsor Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,5,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20101\u20104020\u20106810\u20102_9"},{"key":"e_1_2_10_3_1","unstructured":"FAO.The State of World Fisheries and Aquaculture 2018\u2014Meeting the Sustainable Development Goals. Rome.2018."},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0044\u20108486(99)00086\u20101"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.4172\/2155\u20109546.1000234"},{"key":"e_1_2_10_6_1","unstructured":"FAO.The State of World Fisheries and Aquaculture 2020 Sustainability in Action. Rome.2020."},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/su132112106"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aaf.2021.04.009"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1577\/1548-8659(2002)131<0980:COFPOD>2.0.CO;2"},{"key":"e_1_2_10_10_1","unstructured":"RottmannRW ShiremanJV ChapmanFA.Induction and verification of Triploidy in fish. SRAC Publication No 427 (427) 1\u20132.1991https:\/\/srac.tamu.edu\/serveFactSheet\/90"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1139\/z94\u2010083"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.2478\/aoas\u20102023\u20100044"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/10641269991319162"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2979.2007.00269.x"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-022-02709-5"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2009.04.036"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11160\u2010004\u20108361\u20108"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10126\u2010017\u20109730\u20103"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvex.2009.01.005"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/are\/14312"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2012.06.006"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/hdy.2009.108"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2021.05.004"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2016.04.055"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2016.08.006"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1095\u20108649.2008.01923.x"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1095\u20108649.2012.03479.x"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/10641262.2012.704598"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1006\/jfbi.1997.0505"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.2331\/suisan.56.569"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0229468"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2016.1127"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anbehav.2014.07.028"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166\u20104328(99)00105\u20109"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsos.170989"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anbehav.2014.02.028"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1227412"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2014.66"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/raq.12191"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2018.03.026"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.21315\/tlsr2016.27.2.6"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2021.737249"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2018.04.018"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2018.11.052"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/mec.17039"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep30046"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2024.740582"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.929346"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu12041107"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2019.00454"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2018.03.015"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2015.01359"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2023.109063"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1093\/nutrit\/nuv019"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00009"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0b013e3283572ffa"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12562\u2010011\u20100367\u20102"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2020.e03973"},{"key":"e_1_2_10_59_1","first-page":"1","article-title":"Impact of putative probiotics on growth, behaviour and the gut microbiome of farmed Arctic char (Salvelinus alpinus)","volume":"2544","author":"Knobloch S","year":"2022","journal-title":"Front Microbiol"},{"issue":"1","key":"e_1_2_10_60_1","first-page":"29","article-title":"Effect of bacillus spp. probiotic on growth and feeding performance of rainbow trout (Oncorhynchus mykiss) larvae","volume":"16","author":"Adineh H","year":"2013","journal-title":"Bulg J Vet Med"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2010.0217"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2017.0286"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21207551"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.4025\/actascihealthsci.v43i1.52932"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2017.00074"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.3109\/03009730903573246"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2017.09.020"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10709\u2010014\u20109774\u20105"},{"key":"e_1_2_10_69_1","doi-asserted-by":"crossref","unstructured":"ToewsSD WellbandKW DixonB HeathDD.Variation in juvenile Chinook salmon (Oncorhynchus tshawytscha) transcription profiles among and within eight population crosses from British Columbia Canada.2019.","DOI":"10.1111\/mec.15025"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.2166\/wh.2018.108"},{"issue":"146771","key":"e_1_2_10_71_1","first-page":"1","article-title":"Microbial community and abiotic effects on aquatic bacterial communities in north temperate lakes","volume":"781","author":"Sadeghi J","year":"2021","journal-title":"Sci Total Environ"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-019-0209-9"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3869"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks1219"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009490"},{"key":"e_1_2_10_76_1","volume-title":"R: A Language and Environment for Statistical Computing","author":"Team RC","year":"2016"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/eva.12463"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.10.009"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1095\u20108649.2012.03486.x"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.083550"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anbehav.2013.02.017"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2021.110264"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1998.274.3.r645"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1089\/zeb.2006.3.131"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00083"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41240\u2010019\u20100142\u20103"},{"key":"e_1_2_10_87_1","unstructured":"FinertyC.A Transcriptomics Approach to Examining the Effects of Prenatal and Thermal Stress on Developmental Plasticity in Chinook Salmon (Oncorhynchus Tshawytscha). [MSc Thesis University of Windsor].2020."},{"key":"e_1_2_10_88_1","unstructured":"MayrandJ.Investigating effects of behavioural flexibility and neuroplasticity on acclimation success of outcrossed chinook salmon (Oncorhynchus Tshawytscha): Applications in aquaculture. [MSc Thesis University of Windsor].2017."},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp045"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439\u20100310.2011.01990.x"},{"key":"e_1_2_10_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.applanim.2019.04.014"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.205.14.2005"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anbehav.2017.03.009"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.applanim.2021.105239"},{"key":"e_1_2_10_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.applanim.2010.06.008"},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2003.10.022"},{"key":"e_1_2_10_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2017.10.002"},{"key":"e_1_2_10_98_1","unstructured":"P\u00e9terA.Solomon Coder (Version Beta: 17.03.22): A simple solution for behaviour coding.2017.https:\/\/solomon.andraspeter.com\/"},{"issue":"3514","key":"e_1_2_10_99_1","first-page":"1","article-title":"Analysis of compositions of microbiomes with bias correction","volume":"11","author":"Lin H","year":"2020","journal-title":"Nat Commun"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v067.i01"},{"issue":"2","key":"e_1_2_10_101_1","first-page":"65","article-title":"A simple sequentially Rejective multiple test","volume":"6","author":"Holm S","year":"1979","journal-title":"Scand J Stat"},{"key":"e_1_2_10_102_1","doi-asserted-by":"crossref","unstructured":"G\u00fclsoyG KahveciT.Inferring gene functions from metabolic states.IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS) 2012 IEEE International Workshop on.2012.","DOI":"10.1109\/GENSIPS.2012.6507753"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13253\u2010019\u201000355\u20105"},{"key":"e_1_2_10_104_1","doi-asserted-by":"publisher","DOI":"10.1093\/icb\/icab160"},{"key":"e_1_2_10_105_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb\u20102008\u20109\u20104\u2010215"},{"key":"e_1_2_10_106_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08934"},{"key":"e_1_2_10_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2014.10.017"},{"key":"e_1_2_10_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2008.07.096"},{"key":"e_1_2_10_109_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.hdy.6800941"},{"key":"e_1_2_10_110_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864\u2010016\u20103424\u20105"},{"key":"e_1_2_10_111_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2001.0262"},{"key":"e_1_2_10_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0074\u20107696(05)25004\u20100"},{"key":"e_1_2_10_113_1","doi-asserted-by":"publisher","DOI":"10.1006\/gcen.1998.7058"},{"key":"e_1_2_10_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0044-8486(00)00387-2"},{"key":"e_1_2_10_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquaculture.2006.04.025"},{"key":"e_1_2_10_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2019.12.054"},{"key":"e_1_2_10_117_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740338.2014.872627"},{"key":"e_1_2_10_118_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0173053"},{"key":"e_1_2_10_119_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1422242112"},{"key":"e_1_2_10_120_1","doi-asserted-by":"publisher","DOI":"10.5114\/amos.2015.56342"},{"key":"e_1_2_10_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2004.08.001"},{"key":"e_1_2_10_122_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.153213"},{"key":"e_1_2_10_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2022.104054"},{"key":"e_1_2_10_124_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.204.1.157"},{"key":"e_1_2_10_125_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms3444"},{"key":"e_1_2_10_126_1","doi-asserted-by":"publisher","DOI":"10.1093\/ilar.39.1.20"},{"key":"e_1_2_10_127_1","doi-asserted-by":"publisher","DOI":"10.1139\/cjfas\u20102013\u20100558"},{"key":"e_1_2_10_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.applanim.2020.105031"},{"key":"e_1_2_10_129_1","doi-asserted-by":"publisher","DOI":"10.1139\/f89\u2010033"},{"key":"e_1_2_10_130_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102109.1992.tb00771.x"},{"key":"e_1_2_10_131_1","doi-asserted-by":"publisher","DOI":"10.1111\/jfb.12478"},{"key":"e_1_2_10_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2009.06.022"},{"key":"e_1_2_10_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2012.02.064"},{"key":"e_1_2_10_134_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep18061"},{"key":"e_1_2_10_135_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep33726"},{"key":"e_1_2_10_136_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/9629102"},{"key":"e_1_2_10_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2016.05.040"},{"key":"e_1_2_10_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2010.05.031"},{"key":"e_1_2_10_139_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010genet\u2010110711\u2010155517"},{"key":"e_1_2_10_140_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2017.2742"},{"key":"e_1_2_10_141_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201591206"},{"key":"e_1_2_10_142_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2021.662774"},{"key":"e_1_2_10_143_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2014.125"},{"key":"e_1_2_10_144_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnsyn.2016.00007"},{"key":"e_1_2_10_145_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mp.4000733"},{"key":"e_1_2_10_146_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0060274"},{"key":"e_1_2_10_147_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2014.136"},{"key":"e_1_2_10_148_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.10000278"},{"key":"e_1_2_10_149_1","doi-asserted-by":"publisher","DOI":"10.12717\/DR.2014.18.4.233"},{"key":"e_1_2_10_150_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2017.00035"},{"key":"e_1_2_10_151_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnbeh.2019.00229"},{"key":"e_1_2_10_152_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2019.2922"},{"key":"e_1_2_10_153_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12031\u2010017\u20100996\u20108"}],"container-title":["Genes, Brain and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/gbb.12898","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T03:27:38Z","timestamp":1719372458000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/gbb.12898"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,30]]},"references-count":152,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1111\/gbb.12898"],"URL":"https:\/\/doi.org\/10.1111\/gbb.12898","archive":["Portico"],"relation":{},"ISSN":["1601-1848","1601-183X"],"issn-type":[{"value":"1601-1848","type":"print"},{"value":"1601-183X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,30]]},"assertion":[{"value":"2023-11-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12898"}}