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Here, we synthesized research from three human\u2010dominated landscapes\u2014agricultural, urban, and impounded river systems\u2014to demonstrate that inland waters within these systems exhibit significantly higher GHG emissions compared to their natural or seminatural counterparts. This is particularly evident for CH\n                    <jats:sub>4<\/jats:sub>\n                    and N\n                    <jats:sub>2<\/jats:sub>\n                    O emissions, which show median enhancement ratios of 2.0\u201310 and 2.4\u201313 across the systems, respectively. In contrast, CO\n                    <jats:sub>2<\/jats:sub>\n                    emissions exhibit overall lower enhancement (median enhancement ratios of &lt;\u20092.0\u20133.1), largely due to simultaneously increased photosynthetic uptake from aquatic eutrophication. These observations underscore a clear human footprint on aquatic GHG emissions and the underlying biogeochemical processes. The observed changes in GHG emissions are driven by increased inputs of sediments, carbon, and nutrients from human\u2010disturbed landscapes, coupled with the expansion of aquatic anoxia resulting from increased aquatic metabolism, fine sediment deposition, and eutrophication. Beyond altering emission rates, human activities also modify the abundance and distribution of inland waters, potentially exerting substantial, yet unquantified, effects on landscape\u2010scale GHG emissions. We highlight the importance of understanding these processes for accurately quantifying and mitigating the human footprint on aquatic GHG emissions. Future research and mitigation efforts should account for the variability and mechanisms discussed in this review to effectively address human\u2010induced GHG emissions from inland waters.\n                  <\/jats:p>","DOI":"10.1111\/gcb.70139","type":"journal-article","created":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T06:37:55Z","timestamp":1742279875000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Human Activities Reshape Greenhouse Gas Emissions From Inland Waters"],"prefix":"10.1111","volume":"31","author":[{"given":"Shaoda","family":"Liu","sequence":"first","affiliation":[{"name":"Key Laboratory of Water and Sediment Sciences of Ministry of Education and State Key Laboratory of Regional Environment and Sustainability, School of Environment Beijing Normal University  Beijing 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Ministry of Education and State Key Laboratory of Regional Environment and Sustainability, School of Environment Beijing Normal University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Huang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Water and Sediment Sciences of Ministry of Education and State Key Laboratory of Regional Environment and Sustainability, School of Environment Beijing Normal University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxiu","family":"Zheng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Water and Sediment Sciences of Ministry of Education and State Key Laboratory of Regional Environment and Sustainability, School of Environment Beijing Normal University  Beijing 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