{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:49:44Z","timestamp":1790750984045,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,1,14]],"date-time":"2016-01-14T00:00:00Z","timestamp":1452729600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"FONIS-Ministerio de Salud-CONICYT","award":["SA12I2207"],"award-info":[{"award-number":["SA12I2207"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gerodontology"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study was to determine the efficacy of a chamomile (<jats:italic>Matricaria chamomilla<\/jats:italic>) and linseed (<jats:italic>Linum usitatissimum<\/jats:italic>) saliva substitute in the relief of xerostomia in older participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>In elders, xerostomia is a permanent and progressive condition that significantly affects their quality of life. The treatment for progressive xerostomia is currently restricted to palliative measures, and saliva substitutes are indicated. A lack of evidence on the effectiveness of the saliva substitutes in the relief of symptoms of xerostomia has been reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Seventy\u2010four elderly participants presenting xerostomia of diverse origin were selected. Herbal saliva substitute and carboxymethyl cellulose conventional saliva substitute were tested using a double\u2010blind, randomised, cross\u2010sectional clinical trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Every participant of the study exhibited dry mouth sensation. A sensation of thick saliva was described in 59.5% of the participants. The need for liquid intake to swallow food, the sensation of difficulty in swallowing and the burning sensation in the tongue were observed in 54.1, 56.8 and 27.0% of the participants, respectively. The most prevalent diseases were hypertension, depressive symptoms and arthritis. Results of the clinical tests showed that the herbal saliva substitute produced a greater relief of dry mouth symptoms, thick saliva sensation and the sensation of difficulty in swallowing than the conventional substitute (Wilcoxon test <jats:italic>p<\/jats:italic> &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>New chamomile\u2010 and linseed\u2010based saliva substitute was effective in relieving xerostomia symptoms in older participants of this study.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ger.12220","type":"journal-article","created":{"date-parts":[[2016,1,14]],"date-time":"2016-01-14T13:46:13Z","timestamp":1452779173000},"page":"42-48","source":"Crossref","is-referenced-by-count":33,"title":["Evaluation of the effectiveness of a chamomile (<i>Matricaria chamomilla)<\/i> and linseed (<i>Linum usitatissimum<\/i>) saliva substitute in the relief of xerostomia in elders"],"prefix":"10.1111","volume":"34","author":[{"given":"Irene","family":"Morales\u2010Bozo","sequence":"first","affiliation":[{"name":"Institute for Research in Dental Sciences Faculty of Dentistry University of Chile Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Ortega\u2010Pinto","sequence":"additional","affiliation":[{"name":"Department of Pathology and Oral Medicine Faculty of Dentistry University of Chile Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gonzalo","family":"Rojas Alcayaga","sequence":"additional","affiliation":[{"name":"Department of Pathology and Oral Medicine Faculty of Dentistry University of Chile Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan P.","family":"Aitken Saavedra","sequence":"additional","affiliation":[{"name":"Department of Pathology and Oral Medicine Faculty of Dentistry University of Chile Santiago 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