{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T09:22:56Z","timestamp":1696411376763},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,7,19]],"date-time":"2016-07-19T00:00:00Z","timestamp":1468886400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gerodontology"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Oral bisphosphonates (BP) have been prescribed widely in osteoporosis patients. Bisphosphonate\u2010related osteonecrosis of the jaw (<jats:styled-content style=\"fixed-case\">BRONJ<\/jats:styled-content>) has been reported as a major complication, but there is little information about minor complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This retrospective study describes post\u2010operative complications \u2013 other than <jats:styled-content style=\"fixed-case\">BRONJ<\/jats:styled-content> \u2013 associated with dental extractions in patients on oral <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> and compares outcomes with patients not on oral <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study period was 2004\u201305 ending December 2005, prior to the introduction of protocols for minimising risks related to extractions in patients on <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> therapy. Records of patients aged 60 years and over who underwent extractions during this period at Sydney Dental Hospital were examined and post\u2010operative complications analysed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 266 participants identified on oral <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> therapy out of an available number of 3811 available files based retrospectively from records of 4126 participants who underwent extractions during the two\u2010year period. In the oral <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> group, 10% had complications compared with 2% in the non\u2010oral <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> group (<jats:italic>p<\/jats:italic> &lt; 0.0001). This relationship remained significant even after adjusting for age, gender, operator, type and site of procedure. Delayed healing (36%) and exposed alveolar bone which required an intervention (31%) were the most common complications in the <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The prevalence of minor post\u2010operative complications among <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> participants was significantly higher than in non\u2010<jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> participants. The nature of the complications was in the range of pathology familiar to \u2013 and treatable by \u2013 the general dentist.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ger.12239","type":"journal-article","created":{"date-parts":[[2016,7,20]],"date-time":"2016-07-20T05:01:47Z","timestamp":1468990907000},"page":"171-179","source":"Crossref","is-referenced-by-count":1,"title":["Minor post\u2010extraction complications other than <scp>BRONJ<\/scp> in older patients on oral bisphosphonates \u2013 a retrospective study"],"prefix":"10.1111","volume":"34","author":[{"given":"Russell","family":"Lain","sequence":"first","affiliation":[{"name":"Sydney Local Health District Oral Health Service Sydney Dental Hospital Surry Hills New South Wales Australia"},{"name":"Faculty of Dentistry University of Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shilpi","family":"Ajwani","sequence":"additional","affiliation":[{"name":"Sydney Local Health District Oral Health Service 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