{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T09:00:40Z","timestamp":1781168440603,"version":"3.54.1"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T00:00:00Z","timestamp":1643587200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20H03873"],"award-info":[{"award-number":["20H03873"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20H03899"],"award-info":[{"award-number":["20H03899"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Gerodontology"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To examine the association between oral frailty and oral <jats:italic>Candida<\/jats:italic> carriage as a general indicator of deteriorating oral function in older adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Older adults exhibit an elevated risk of oral candidiasis caused by <jats:italic>Candida<\/jats:italic>. Although many studies have identified factors associated with oral <jats:italic>Candida<\/jats:italic> carriage, none have evaluated its relationship with oral function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>This study included 210 community\u2010dwelling older adults aged \u226560\u00a0years who participated in wellness checks. Fungal flora expression in saliva samples was evaluated to identify oral <jats:italic>C.\u00a0albicans<\/jats:italic> and <jats:italic>C.\u00a0glabrata<\/jats:italic>. Participants were categorised by detection of neither strain (group 1), either one of the strains (group 2), or both strains (group 3). The relationship between oral <jats:italic>Candida<\/jats:italic> carriage and oral frailty was evaluated by multinomial logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The participants included 58 men and 152 women with a mean age of 74.2\u00a0\u00b1\u00a06.1\u00a0years. A total of 88 (41.9%), 94 (44.8%) and 28 (13.3%) participants were assigned to groups 1, 2 and 3 respectively. In the multinomial logistic regression analysis, significant associations were observed between group 1 and group 2 for \u201cHave you choked on your tea or soup recently?\u201d and the number of applicable oral frailty items. Between group 1 and group 3, significant associations were observed for the number of remaining teeth, masticatory performance and the number of applicable oral frailty items.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We obtained basic data useful for intervention studies aimed at verifying whether oral function management prevents deterioration of the oral bacterial flora.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ger.12621","type":"journal-article","created":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T09:48:55Z","timestamp":1643622535000},"page":"49-58","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Oral frailty and carriage of oral <i>Candida<\/i> in community\u2010dwelling older adults (Check\u2010up to discover Health with Energy for senior Residents in Iwamizawa; CHEER Iwamizawa)"],"prefix":"10.1111","volume":"39","author":[{"given":"Haruhisa","family":"Baba","sequence":"first","affiliation":[{"name":"Gerodontology Department of Oral Health Science Faculty of Dental Medicine Hokkaido University Sapporo City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4983-2399","authenticated-orcid":false,"given":"Yutaka","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Gerodontology Department of Oral Health Science Faculty of Dental Medicine Hokkaido University Sapporo City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhito","family":"Miura","sequence":"additional","affiliation":[{"name":"Gerodontology Department of Oral Health Science Faculty of Dental Medicine Hokkaido University Sapporo City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimiya","family":"Ozaki","sequence":"additional","affiliation":[{"name":"Gerodontology Department 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