{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T04:11:33Z","timestamp":1788927093372,"version":"build-2803163510"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,7,26]],"date-time":"2023-07-26T00:00:00Z","timestamp":1690329600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Gerodontology"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Metastatic tumours of bone must be considered in all patients with unexplained bone pain and particularly in patients who present with a known cancer, localised pain at multiple sites, and radiographic findings suggestive of metastasis. The purpose of this report was to present a case of a pathological fracture of the mandible as a consequence of metastatic pulmonary adenocarcinoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>In July 2018 a 68\u2010year\u2010old male patient was hospitalised because of pulmonary adenocarcinoma and attended our department for an oral maxillo\u2010facial evaluation. He complained of pain and swelling in the right temporomandibular region resulting in a reported functional limitation.<\/jats:p><jats:p>An Orthopantomogram (OPG) demonstrated a right intracapsular condylar compound fracture associated with an osteolytic lesion at the condyle base with jagged margins. Subsequently, a CT scan with contrast of the maxillo\u2010facial complex and a fine\u2010needle aspiration of the lesion was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>CT images showed the presence of a right mandibular condyle fracture associated with a large osteolytic lesion which confirmed the pathological nature of the fracture. Fine\u2010needle aspiration of the lesion confirmed its metastatic nature. It was not possible to proceed with a mandibular resection due to the critical clinical condition of the patient who died in September 2018.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Lung cancer frequently produces lytic\u2010type metastasis, sometimes even in the jaw. In patients with an established diagnosis of lung cancer, any radiolucent lesion of the jaw or an unexplained painful symptomatology to the oro\u2010maxillo facial complex should be placed in differential diagnosis with metastasis of the primary tumour.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ger.12707","type":"journal-article","created":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T05:30:40Z","timestamp":1690435840000},"page":"283-288","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Mandibular metastasis of pulmonary adenocarcinoma: How unexpected could it be?"],"prefix":"10.1111","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8478-5735","authenticated-orcid":false,"given":"Erica","family":"Vettori","sequence":"first","affiliation":[{"name":"Unit of Maxillofacial Surgery and Stomatology, Department of Medical, Surgical and Health Sciences University of Trieste  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Borella","sequence":"additional","affiliation":[{"name":"Unit of Maxillofacial Surgery and Stomatology, Department of Medical, Surgical and Health Sciences University of Trieste  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fulvia","family":"Costantinides","sequence":"additional","affiliation":[{"name":"Unit of Maxillofacial Surgery and Stomatology, Department of Medical, Surgical and Health Sciences University of Trieste  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Rizzo","sequence":"additional","affiliation":[{"name":"Unit of Maxillofacial Surgery and Stomatology, Department of Medical, Surgical and Health Sciences University of Trieste  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Maglione","sequence":"additional","affiliation":[{"name":"Unit of Maxillofacial Surgery and Stomatology, Department of Medical, Surgical and Health Sciences University of Trieste  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,26]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"IARC\u2010International Agency for Research on Cancerhttps:\/\/gco.iarc.fr\/today\/data\/factsheets\/cancers\/15\u2010Lung\u2010fact\u2010sheet.pdf"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2018.12.006"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.21037\/tlcr.2020.03.11"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.18632\/aging.202292"},{"issue":"1","key":"e_1_2_9_6_1","first-page":"56","article-title":"Lung cancer: diagnosis and management","volume":"75","author":"Collins LG","year":"2007","journal-title":"Am Fam Physician"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3934\/mbe.2020038"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2013.0084"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21166"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(19)39389-4"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0121323"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2014.01.009"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sult.2018.11.009"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-24223-1_1"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e318206a221"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.00715"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezz384"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S28339"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jormas.2021.12.009"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13611"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2007.09.012"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-007-0321-2"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(89)90286-3"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-198668020-00021"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-029X.110737"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000010296"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-014-0591-z"},{"issue":"3","key":"e_1_2_9_28_1","first-page":"287","article-title":"Metastasis of lung adenocarcinoma to the gingiva: a rare case report. Iran","volume":"40","author":"Rajini Kanth M","year":"2015","journal-title":"J Med Sci"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2018-227862"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.4329\/wjr.v7.i8.202"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/iju.13170"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S87568"},{"issue":"4","key":"e_1_2_9_33_1","first-page":"198","article-title":"Condylar metastasis with initial presentation as TMJ syndrome","volume":"40","author":"Owen DG","year":"1985","journal-title":"J Oral Med"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-160X-4-8"}],"container-title":["Gerodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ger.12707","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T05:31:58Z","timestamp":1716183118000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ger.12707"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,26]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1111\/ger.12707"],"URL":"https:\/\/doi.org\/10.1111\/ger.12707","archive":["Portico"],"relation":{},"ISSN":["0734-0664","1741-2358"],"issn-type":[{"value":"0734-0664","type":"print"},{"value":"1741-2358","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,26]]},"assertion":[{"value":"2023-07-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}