{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:10:14Z","timestamp":1773015014386,"version":"3.50.1"},"reference-count":57,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100006162","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Ci\u00eancia e Tecnologia do Estado de Pernambuco","doi-asserted-by":"publisher","award":["IBPG\u20100075\u20104.02\/23"],"award-info":[{"award-number":["IBPG\u20100075\u20104.02\/23"]}],"id":[{"id":"10.13039\/501100006162","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Gerodontology"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aims to map the existing literature on natural products used as disinfection substances for conventional polymethyl methacrylate (PMMA) and computer\u2010aided design and manufacturing (CAD\u2010CAM) dentures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Denture wearers are at high risk for denture stomatitis. Natural products have attracted the interest of the scientific community as an alternative to synthetic ones.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>The guiding question \u201cWhich natural products have been applied to disinfect complete dentures in conventional PMMA or CAD\u2010CAM PMMA resin?\u201d Searches were conducted in the PubMed\/MEDLINE, Embase, Web of Science, and Cochrane databases, and manual searches were performed in reference journals in the area with studies published until December 2023, without language or date restrictions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 4272 articles were identified, and 46 studies were included after applying the eligibility criteria. Thirty\u2010nine natural products were evaluated. Of the included studies, 43 presented positive findings and three obtained negative findings on the effectiveness of natural products in inhibiting or killing\n                      <jats:italic>Candida albicans<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Natural products, predominantly sourced from the Plantae kingdom, have demonstrated efficacy in reducing\n                      <jats:italic>Candida albicans<\/jats:italic>\n                      on the surface of conventional PMMA. However, the evidence primarily stems from in\u00a0vitro studies, underscoring the necessity for additional clinical research to validate their applicability under real microbiological conditions in prosthesis users.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ger.12783","type":"journal-article","created":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T06:19:53Z","timestamp":1730873993000},"page":"12-26","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Natural products for denture base disinfection: A scoping review"],"prefix":"10.1111","volume":"42","author":[{"given":"Bianca Lopes de Andrade Martins","family":"de Lima","sequence":"first","affiliation":[{"name":"Department of Oral Rehabilitation University of Pernambuco (UPE) Faculty of Dentistry  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeferson Batista","family":"Santiago","sequence":"additional","affiliation":[{"name":"Department of Oral Rehabilitation University of Pernambuco (UPE) Faculty of Dentistry  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Eduarda Lemos","family":"Avelino","sequence":"additional","affiliation":[{"name":"Department of Oral Rehabilitation University of Pernambuco (UPE) Faculty of Dentistry  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taciana Em\u00edlia Leite","family":"Vila\u2010Nova","sequence":"additional","affiliation":[{"name":"Department of Oral Rehabilitation University of Pernambuco (UPE) Faculty of Dentistry  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rayanna Thayse Flor\u00eancio","family":"Costa","sequence":"additional","affiliation":[{"name":"Department of Oral Rehabilitation University of Pernambuco (UPE) Faculty of Dentistry  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3154-5092","authenticated-orcid":false,"given":"Sandra L\u00facia Dantas","family":"Moraes","sequence":"additional","affiliation":[{"name":"Department of Oral Rehabilitation University of Pernambuco (UPE) Faculty of Dentistry  Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,6]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-7757-2016-0222"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/ger.12176"},{"key":"e_1_2_11_4_1","first-page":"1","article-title":"Evaluating the efficiency of humic acid micro\u2010organisms from denture base material","volume":"33","author":"Meri\u00e7 G","year":"2014","journal-title":"Gerodontology"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016357.2016.1166261"},{"key":"e_1_2_11_6_1","unstructured":"Gulce \u00c7akmakMBD.Effect of thermocycling on the flexural strength and hardness of new\u2010generation denture base materials. 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