{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T14:51:40Z","timestamp":1776437500824,"version":"3.51.2"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Gerodontology"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study investigated the associations between baseline n\u20106 and n\u20103 polyunsaturated fatty acid levels and the number of teeth lost subsequently over 5\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The relationship between n\u20103 and n\u20106 polyunsaturated fatty acids and tooth loss remains unclear. Previous studies have been limited to older individuals aged 70 and above, and no research has been conducted that takes into account a broader age range.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>\n                      Participants (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091534) attended both the baseline survey and the follow\u2010up survey conducted 5\u2009years later. Poisson regression analyses were conducted after converting the number of teeth present at baseline into an adjustment variable. The dependent variable was the number of lost teeth over a five\u2010year period. The exposure variables were each quintile of self\u2010reported n\u20103 and n\u20106 polyunsaturated fatty acid intake levels (g\/1000\u2009kcal) and the ratio of self\u2010reported n\u20106 to n\u20103 polyunsaturated fatty acid intake levels (n\u20106:n\u20103 ratio) adjusted by age, sex, smoking, use of dental floss or interdental brush and history of diabetes mellitus.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Higher n\u20103 fatty acid intake (5th quintile, incidence rate ratio (IRR): 0.21,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and a lower dietary n\u20106:n\u20103 ratio (\u2264\u20094.0) significantly lower tooth loss risk. Conversely, higher n\u20106 intake (5th quintile, IRR: 1.32,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) was associated with the likelihood of tooth loss. Younger age, flossing and adequate chewing ability were associated with better dental outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Balanced dietary intake, particularly higher n\u20103 fatty acids and a lower n\u20106:n\u20103 ratio, helps preserve dental health by reducing tooth loss risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ger.12819","type":"journal-article","created":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T12:41:00Z","timestamp":1743856860000},"page":"521-528","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dietary n\u20106 and n\u20103 Polyunsaturated Fatty Acids and Tooth Loss in Community\u2010Dwelling Older Japanese People"],"prefix":"10.1111","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0424-8228","authenticated-orcid":false,"given":"Akihiro","family":"Yoshihara","sequence":"first","affiliation":[{"name":"Faculty of Dentistry and Graduate School of Medical and Dental Sciences, Division of Oral Science for Health Promotion Niigata University  Niigata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5739-2936","authenticated-orcid":false,"given":"Masanori","family":"Iwasaki","sequence":"additional","affiliation":[{"name":"Division of Preventive Dentistry, Graduate School of Dental Medicine Hokkaido University  Sapporo Hokkaido Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kana","family":"Suwama","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry and Graduate School of Medical and Dental Sciences, Division of Oral Science for Health Promotion Niigata University  Niigata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayuko","family":"Odajima","sequence":"additional","affiliation":[{"name":"Faculty of Dentistry and Graduate School of Medical and Dental Sciences, Division of Oral Science for Health Promotion Niigata University  Niigata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Kabasawa","sequence":"additional","affiliation":[{"name":"Department of Health Promotion Medicine Niigata University Graduate School of Medical and Dental Sciences  Niigata Japan"},{"name":"Division of Clinical Nephrology and Rheumatology, Kidney Research Center Niigata University Graduate School of Medical and Dental Sciences  Niigata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumi","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Health Promotion Medicine Niigata University Graduate School of Medical and Dental Sciences  Niigata Japan"},{"name":"Division 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