{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:40:43Z","timestamp":1790887243516,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:00:00Z","timestamp":1774310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:00:00Z","timestamp":1774310400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Gerodontology"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to clinically validate the Oral Frailty Five\u2010item Checklist (OF\u20105) by clarifying the relationship between its score and the diagnosis of oral dysfunction, as well as its association with seven sub\u2010items.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Assessing oral frailty is important for preventing frailty in older adults. The recently developed OF\u20105 is anticipated as a convenient screening tool; however, its relationship with oral hypofunction, assessed through quantitative testing in dental clinics, has not been sufficiently verified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials &amp; Methods<\/jats:title>\n                    <jats:p>The study included 421 outpatients aged 65\u2009years or older who underwent their first oral hypofunction test at a university dental hospital. Data on age, sex, OF\u20105 score, and oral hypofunction test values (oral hygiene, oral dryness, occlusal force, tongue\u2010lip motor function, tongue pressure, masticatory function, and swallowing function) were extracted from medical records and analyzed using multivariate analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The age of the participants was 80.9\u2009\u00b1\u20096.5 (mean\u2009\u00b1\u2009standard deviation) years, and 254 (60.3%) were female. Logistic regression analysis showed that the OF\u20105 score was significantly associated with the diagnosis of oral hypofunction (odds ratio: 2.54), with a cutoff value of 2 points. Multiple regression analysis showed significant associations between the OF\u20105 and all test components except oral hygiene.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The OF\u20105 is a useful screening test for oral hypofunction, involving masticatory, swallowing, and tongue dysfunction and oral dryness. However, there is also a need for dental examination to identify poor oral hygiene, which cannot be detected using the OF\u20105 test.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ger.70071","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T09:53:03Z","timestamp":1774345983000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical Validity of the Oral Frailty Five\u2010Item Checklist (\n                    <scp>OF<\/scp>\n                    \u20105) for the Diagnosis of Oral Hypofunction"],"prefix":"10.1111","author":[{"given":"Tomohiro","family":"Tabata","sequence":"first","affiliation":[{"name":"Department of Oral Function Management, Graduate School of Dentistry Showa Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukiko","family":"Hatanaka","sequence":"additional","affiliation":[{"name":"Department of Oral Function Management, Graduate School of Dentistry Showa Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masatsugu","family":"Teraoka","sequence":"additional","affiliation":[{"name":"Department of Oral Function Management, Graduate School of Dentistry Showa Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mana","family":"Hirayama","sequence":"additional","affiliation":[{"name":"Department of Oral Function Management, Graduate School of Dentistry Showa Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Koyanagi","sequence":"additional","affiliation":[{"name":"Department of Oral Function Management, Graduate School of Dentistry Showa Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Housei","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Oral Function Management, Graduate School of Dentistry Showa Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8018-4537","authenticated-orcid":false,"given":"Junichi","family":"Furuya","sequence":"additional","affiliation":[{"name":"Department of Oral Function Management, Graduate School of Dentistry Showa Medical University  Tokyo 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