{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T19:56:15Z","timestamp":1775159775680,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,11,11]],"date-time":"2013-11-11T00:00:00Z","timestamp":1384128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Lichen planus is a T\u2009cell\u2010mediated chronic inflammatory disease of unknown etiology. The objective of the present study was to evaluate the status of oxidative stress in saliva and the anti\u2010oxidant defense system in relation to quality of life parameters in patients with oral lichen planus (<jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The sample consisted of 70 patients (40 with <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> and 30 control patients). The average age of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> patients was 60\u2009years (9 males and 31 females), and of the control group 57\u2009years (6 males and 24 females). All participants completed the Oral Health Impact Profile\u201049 quality of life questionnaire. Total anti\u2010oxidant activity and lipid peroxidation products in saliva were evaluated, using ferric reducing anti\u2010oxidant power and thiobarbituric acid reactive substance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean levels of salivary malondialdehyde were higher in the <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> group than the control group (<jats:italic>P<\/jats:italic>\u2009=\u20090.001), and total anti\u2010oxidant capacity was lower among <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> patients than control patients (<jats:italic>P<\/jats:italic>\u2009=\u20090.02). There was no correlation between Oral Health Impact Profile\u201049 findings and the oxidative stress parameters studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results of the present study point to the possible function of oxidative stress in the etiopathogenesis of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>. <jats:bold>Geriatr Gerontol Int 2014; 14: 654\u2013659.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.12153","type":"journal-article","created":{"date-parts":[[2013,11,11]],"date-time":"2013-11-11T08:08:45Z","timestamp":1384157325000},"page":"654-659","source":"Crossref","is-referenced-by-count":35,"title":["Salivary biomarkers of oxidative stress and quality of life in patients with oral lichen planus"],"prefix":"10.1111","volume":"14","author":[{"given":"Pia","family":"Lopez\u2010Jornet","sequence":"first","affiliation":[{"name":"Oral Medicine Ageing Research Institute Faculty of Medicine and Dentistry University of Murcia  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ascension","family":"Martinez\u2010Canovas","sequence":"additional","affiliation":[{"name":"Oral Medicine Ageing Research Institute Faculty of Medicine and Dentistry University of Murcia  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alvaro","family":"Pons\u2010Fuster","sequence":"additional","affiliation":[{"name":"Oral Medicine Ageing Research Institute Faculty of Medicine and Dentistry University of Murcia  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,11,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2007.07.199"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2010.00894.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2010.00946.x"},{"key":"e_1_2_6_5_1","first-page":"E310","article-title":"Oral lichen planus and oral lichenoid lesions; 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