{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T12:11:35Z","timestamp":1789906295391,"version":"4.0.1"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,1,8]],"date-time":"2014-01-08T00:00:00Z","timestamp":1389139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"CIEN Foundation, Spain","award":["PI 017\/09"],"award-info":[{"award-number":["PI 017\/09"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed at analyzing the effect of quality of life (<jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content>) on mortality in older adults with dementia living in long\u2010term care facilities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective observational cohort study was carried out on 412 residents aged older than 60 years, diagnosed with dementia according to the <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>iagnostic and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tatistical <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>anual of <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ental <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>isorders, fourth edition. Besides assessment of <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">EQ\u20105D<\/jats:styled-content> index by proxy) and perceived health status (<jats:styled-content style=\"fixed-case\">EQ\u2010VAS<\/jats:styled-content>), baseline measurements included severity of dementia (<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>linical <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ementia <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>ating <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cale [<jats:styled-content style=\"fixed-case\">CDR<\/jats:styled-content>]), comorbidity (number of self\u2010reported chronic conditions), disability evaluation (<jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>arthel Index), cognitive state (<jats:styled-content style=\"fixed-case\"><jats:italic>Mini Examen Cognoscitivo<\/jats:italic><\/jats:styled-content>, a validated and modified <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>panish version of the <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ini\u2010<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ental <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tate <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>xamination) and depression (<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ornell <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>epression <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>cale for <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ementia). Sociodemographic and clinical variables were analyzed as potential effect modifiers and confounders in the relationship between <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content> and mortality using a multivariate logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After an 18\u2010month follow up, 138 residents had died. Adjusting for <jats:styled-content style=\"fixed-case\">CDR<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>arthel Index, the odds of mortality were multiplied by 0.25 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.09\u20130.70) and 0.79 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.26\u20132.42) for every unit of change in the <jats:styled-content style=\"fixed-case\">EQ\u20105D<\/jats:styled-content> index in the residents with <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ornell score &lt;6 and \u22656, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present study suggests that the effect of <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content> on mortality in institutionalized adults with dementia should take into account the presence or absence of depression. In addition, residents with a greater disability and more advanced dementia should be a target for interventions in rehabilitation care. <jats:bold>Geriatr Gerontol Int 2015; 15: 38\u201344.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.12225","type":"journal-article","created":{"date-parts":[[2014,1,8]],"date-time":"2014-01-08T11:07:18Z","timestamp":1389179238000},"page":"38-44","source":"Crossref","is-referenced-by-count":18,"title":["Quality of life by proxy and mortality in institutionalized older adults with dementia"],"prefix":"10.1111","volume":"15","author":[{"given":"Abel E","family":"Gonz\u00e1lez\u2010V\u00e9lez","sequence":"first","affiliation":[{"name":"Service of Preventive Medicine University Hospital Ram\u00f3n y Cajal  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Joao","family":"Forjaz","sequence":"additional","affiliation":[{"name":"National School of Public Health and REDISSEC Carlos III Institute of Health  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Giraldez\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"Service of Preventive Medicine University Hospital La Paz  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salom\u00e9","family":"Mart\u00edn\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"EULEN Socio\u2010sanitary Services  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Mart\u00ednez\u2010Mart\u00edn","sequence":"additional","affiliation":[{"name":"Alzheimer Disease Research Unit and CIBERNED, Alzheimer Center Reina Sofia Foundation Carlos III Institute of Health  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Spanish Research Group on Quality of Life and Ageing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,1,8]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67889-0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2004.52058.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2010.01398.x"},{"issue":"11","key":"e_1_2_7_5_1","first-page":"S16","article-title":"Prognosis with dementia in Europe: a collaborative study of population\u2010based cohorts. 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