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The purpose of the present study was to describe the factors related to health conditions and residential environment that influence <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> of older adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from 1815 cases came from three cross\u2010sectional surveys on quality of life in older adults in <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>pain: non\u2010institutionalized older adults (<jats:italic>n<\/jats:italic>\u2009=\u20091106), institutionalized older adults without dementia (<jats:italic>n<\/jats:italic>\u2009=\u2009234) and institutionalized older adults with dementia (<jats:italic>n<\/jats:italic>\u2009=\u2009475). Assessment instruments used were: <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>arthel <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndex, <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>hort <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ortable <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ental <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tatus <jats:styled-content style=\"fixed-case\">Q<\/jats:styled-content>uestionnaire, <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>omorbidity <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndex, <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">5D<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">3L<\/jats:styled-content> (5 dimensions, <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u2010index and <jats:styled-content style=\"fixed-case\">EQ\u2010VAS<\/jats:styled-content>), and information about sociodemographic characteristics and social networks. Partial correlation and multivariate logistic regression analyses were carried out.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In group comparisons, institutionalized older adults showed a higher percentage of problems in the <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">5D<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">3L<\/jats:styled-content> dimensions than the non\u2010institutionalized ones. Also, older adults with dementia presented less pain\/discomfort and anxiety\/depression than the other groups, but showed more problems in mobility, self\u2010care and usual activities. <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u2010Index showed a high association with functional independence, perceived health status and comorbidity. According to the logistic regression models, the Barthel Index was the most common determinant for most of <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">5D<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">3L<\/jats:styled-content> dimensions in all groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Institutionalized older adults with dementia presented lower <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> than the other groups. Functional independence, comorbidity and cognitive status were the main <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> determinants in all groups. Maintenance and improvement of the functional condition might be translated into a higher <jats:styled-content style=\"fixed-case\">HRQOL<\/jats:styled-content> of older adults. <jats:bold>Geriatr Gerontol Int 2015; 15: 627\u2013635.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.12325","type":"journal-article","created":{"date-parts":[[2014,8,11]],"date-time":"2014-08-11T11:45:49Z","timestamp":1407757549000},"page":"627-635","source":"Crossref","is-referenced-by-count":29,"title":["Quality of life across three groups of older adults differing in cognitive status and place of residence"],"prefix":"10.1111","volume":"15","author":[{"given":"Beatriz","family":"Le\u00f3n\u2010Salas","sequence":"first","affiliation":[{"name":"Alzheimer Disease Research Unit CIEN Foundation Carlos III Institute of Health, Alzheimer Center Reina Sofia Foundation  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alba","family":"Ayala","sequence":"additional","affiliation":[{"name":"National School of Public Health Carlos III Institute of Health and REDISSEC  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vendula","family":"Blaya\u2010Nov\u00e1kov\u00e1","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine and Quality Management Gregorio Mara\u00f1\u00f3n General University Hospital  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Avila\u2010Villanueva","sequence":"additional","affiliation":[{"name":"Alzheimer Disease Research Unit CIEN Foundation Carlos III Institute of Health, Alzheimer Center Reina Sofia Foundation  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Rodr\u00edguez\u2010Bl\u00e1zquez","sequence":"additional","affiliation":[{"name":"National Center of Epidemiology Carlos III Institute of Health Consortium for Biomedical Research in Neurodegenerative Disease (CIBERNED) Spanish National Research Council  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fermina","family":"Rojo\u2010P\u00e9rez","sequence":"additional","affiliation":[{"name":"Institute of Economics, Geography and Demography Center for Human and Social Sciences Spanish National Research Council  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Fern\u00e1ndez\u2010Mayoralas","sequence":"additional","affiliation":[{"name":"Institute of Economics, Geography and Demography Center for Human and Social Sciences Spanish National Research Council  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Mart\u00ednez\u2010Mart\u00edn","sequence":"additional","affiliation":[{"name":"National Center of Epidemiology Carlos III Institute of Health Consortium for Biomedical Research in Neurodegenerative Disease (CIBERNED) Spanish National Research Council  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Jo\u00e3o","family":"Forjaz","sequence":"additional","affiliation":[{"name":"National School of Public Health Carlos III Institute of Health and REDISSEC  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Spanish Research Group on Quality of Life and Aging","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,8,11]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Active Ageing: A Policy Framework","author":"World Health Organization","year":"2002"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1547-5069.2005.00058.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2012.11.006"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1999.tb02571.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102377\u20109\u201055."},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002093-199404000-00015"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/39.1.25"},{"issue":"3","key":"e_1_2_7_9_1","first-page":"56","article-title":"Quality\u2010of\u2010life assessment in dementia drug development. 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