{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T02:09:50Z","timestamp":1791252590644,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,11,3]],"date-time":"2014-11-03T00:00:00Z","timestamp":1414972800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Health and Labour Sciences Research Grants","award":["Comprehensive Research on Aging and Health"],"award-info":[{"award-number":["Comprehensive Research on Aging and Health"]}]},{"name":"Research Funding for Longevity Sciences","award":["22-16"],"award-info":[{"award-number":["22-16"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To examine the association of the combination of slow gait and mild cognitive impairment (<jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>) with cognitive function and falling in community\u2010dwelling older people.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants were selected from the <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>bu <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tudy of <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ealth <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>romotion for the <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>lderly (<jats:italic>n<\/jats:italic>\u2009=\u20093400), and underwent gait examination and a battery of neuropsychological examinations, including the <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ini\u2010<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ental <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tate <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>xamination and the <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ational <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>enter for <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>eriatrics and <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>erontology <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>unctional <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ssessment <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>ool (tablet version of <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>rail <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>aking <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>est <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>art <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ymbol <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>igit <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ubstitution <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>ask, Figure selection task, <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>ord memory and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tory memory), and were interviewed with a series of questionnaires including medical history, physical activity, geriatric depression scale and fall history.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Participants were classified into control (<jats:italic>n<\/jats:italic>\u2009=\u20092281), slow gait speed (<jats:styled-content style=\"fixed-case\">SG<\/jats:styled-content>; <jats:italic>n<\/jats:italic>\u2009=\u2009278), <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u2009=\u2009673) and <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">SG<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">SG<\/jats:styled-content>; <jats:italic>n<\/jats:italic>\u2009=\u2009168) groups. All cognitive functions were significantly affected by the group factor, even adjusting for participant characteristics as covariates (<jats:styled-content style=\"fixed-case\"><jats:italic>P<\/jats:italic>\u2009<\/jats:styled-content>&lt;<jats:styled-content style=\"fixed-case\">\u20090<\/jats:styled-content>.001). Post\u2010hoc analysis showed that the control group had better performance than the other groups, and the <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">SG<\/jats:styled-content> group had worse performance than the other groups in all cognitive functions (all <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). In multiple logistic regression analysis, <jats:styled-content style=\"fixed-case\">SG<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content> were independently associated with falling (all <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05), and <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">SG<\/jats:styled-content> had a higher odds ratio for falling (adjusted <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.99, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.08\u20133.65).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings support the idea that slow gait and <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content> were related, and concurrently associated with falling. Motor function among <jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content> subjects should be focused on to assess profile risks. <jats:bold>Geriatr <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>erontol <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>nt 2015; 15: 1073\u20131078.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.12407","type":"journal-article","created":{"date-parts":[[2014,11,3]],"date-time":"2014-11-03T10:06:35Z","timestamp":1415009195000},"page":"1073-1078","source":"Crossref","is-referenced-by-count":67,"title":["Cognitive function and falling among older adults with mild cognitive impairment and slow gait"],"prefix":"10.1111","volume":"15","author":[{"given":"Takehiko","family":"Doi","sequence":"first","affiliation":[{"name":"Department of Functioning Activation Center for Gerontology and Social Science National Center for Geriatrics and Gerontology  Obu Aichi Japan"},{"name":"Research Institute National 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