{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T04:35:37Z","timestamp":1773203737543,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,9,3]],"date-time":"2015-09-03T00:00:00Z","timestamp":1441238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>The purpose of the present study was to evaluate whether a diagnosis of dementia before stroke onset (pre\u2010stroke dementia [<jats:styled-content style=\"fixed-case\">PSD]<\/jats:styled-content>) affects the short\u2010term functional outcome of elderly ischemic stroke patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective case\u2013control study comprising of consecutive elderly ischemic stroke patients. Functional outcome was assessed by the <jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>unctional <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>ndependence <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>easure scale (<jats:styled-content style=\"fixed-case\">FIM<\/jats:styled-content>) at admission and discharge. Data was analyzed by <jats:italic>t<\/jats:italic>\u2010test, \u03c7<jats:sup>2<\/jats:sup>\u2010test, multiple linear regression analysis and logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 919 patients with acute ischemic stroke, out of whom 11.5% were diagnosed with <jats:styled-content style=\"fixed-case\">PSD<\/jats:styled-content> on index day. Compared with non\u2010<jats:styled-content style=\"fixed-case\">PSD<\/jats:styled-content> patients, those with pre\u2010stroke dementia had a shorter length of stay (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), higher rate of female patients (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and lower <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ini\u2010<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ental <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tate <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>xamination scores (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Both total and motor <jats:styled-content style=\"fixed-case\">FIM<\/jats:styled-content> scores at admission and discharge, and their respective <jats:styled-content style=\"fixed-case\">FIM<\/jats:styled-content> gain scores at discharge were higher in non\u2010<jats:styled-content style=\"fixed-case\">PSD<\/jats:styled-content> compared with <jats:styled-content style=\"fixed-case\">PSD<\/jats:styled-content> patients (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). In logistic regression analysis to identify factors predicting successful outcome (defined as total <jats:styled-content style=\"fixed-case\">FIM<\/jats:styled-content> at discharge \u226580), <jats:styled-content style=\"fixed-case\">PSD<\/jats:styled-content> remained as significantly associated with increased risk for adverse outcome on discharge (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 2.449, <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.207\u20134.970, <jats:italic>P<\/jats:italic>\u2009=\u20090.013).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The present findings suggest that a diagnosis of pre\u2010stroke dementia is associated with lower <jats:styled-content style=\"fixed-case\">FIM<\/jats:styled-content> scores at admission and discharge in patients with ischemic stroke. Yet, daily motor <jats:styled-content style=\"fixed-case\">FIM<\/jats:styled-content> gains were similar in <jats:styled-content style=\"fixed-case\">PSD<\/jats:styled-content> and non\u2010<jats:styled-content style=\"fixed-case\">PSD<\/jats:styled-content> patients, suggesting that these patients should not be deprived of a post\u2010acute rehabilitation, based on a diagnosis of dementia before stroke onset. <jats:bold>Geriatr Gerontol Int 2016; 16: 928\u2013933.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.12574","type":"journal-article","created":{"date-parts":[[2015,9,4]],"date-time":"2015-09-04T03:33:14Z","timestamp":1441337594000},"page":"928-933","source":"Crossref","is-referenced-by-count":18,"title":["Pre\u2010stroke dementia does not affect the post\u2010acute care functional outcome of old patients with ischemic stroke"],"prefix":"10.1111","volume":"16","author":[{"given":"Eliyahu\u2010Hayim","family":"Mizrahi","sequence":"first","affiliation":[{"name":"Department of Geriatric Medicine and Rehabilitation Shmuel Harofe Hospital  Beer\u2010Yaakov Israel"},{"name":"The Sackler School of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Arad","sequence":"additional","affiliation":[{"name":"The Sackler School of Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Geriatric Medicine and Rehabilitation Sheba Medical Center  Tel\u2010Hashomer Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abraham","family":"Adunsky","sequence":"additional","affiliation":[{"name":"The Sackler School of Medicine Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Geriatric Medicine and Rehabilitation Sheba Medical Center  Tel\u2010Hashomer Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70025-0"},{"key":"e_1_2_6_3_1","unstructured":"World Health Organization.Major burden of disease\u2010leading 10 selected risk factors and leading 10 diseases and injuries in developed countries with low mortality levels. The World Health Report 2002 Statistical Annex Annex 16 June2007."},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0909087"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182a35151"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.28.12.2429"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000017285.73172.91"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2009.09.010"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afn282"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269881113495118"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.59.4.537"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afm132"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-012-6508-4"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-4-34"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.162.15.1753"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9993(94)90384-0"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9993(93)90119-U"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.7.939"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.2.250"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.56.1.33"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.16.2.178"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.35.1.39"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1053\/apmr.2002.32739"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638280600787096"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102013\u2010003105"}],"container-title":["Geriatrics &amp; Gerontology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fggi.12574","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ggi.12574","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T16:14:39Z","timestamp":1695485679000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ggi.12574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,3]]},"references-count":25,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["10.1111\/ggi.12574"],"URL":"https:\/\/doi.org\/10.1111\/ggi.12574","archive":["Portico"],"relation":{},"ISSN":["1444-1586","1447-0594"],"issn-type":[{"value":"1444-1586","type":"print"},{"value":"1447-0594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,3]]}}}