{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T06:08:07Z","timestamp":1785305287249,"version":"3.55.0"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T00:00:00Z","timestamp":1450656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>The Mobility and Independent Living in Elders Study (<jats:styled-content style=\"fixed-case\">MILES<\/jats:styled-content>) was established in 2012 to estimate the prevalence, incidence, and risk factors for disability and age\u2010related disease in rural older Indians. Here we describe the main goals of <jats:styled-content style=\"fixed-case\">MILES<\/jats:styled-content>, the essential elements of its design and examinations, and the initial findings from the baseline visit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A random sample of 562 men and women aged \u226560 years was enrolled from the <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>edchal region in <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>elangana <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>tate. Baseline examination consisted of two separate clinical visits, and included measurements of blood pressure, anthropometry, physical function, peripheral artery disease, cognitive function, bone and muscle quality, knee osteoarthritis, carotid intima\u2010media thickness, and blood biomarkers. A comprehensive interview was carried out for demographics, disability and disease history. Annual follow\u2010up visits are ongoing to collect information on incident disability and disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median age of participants was 66 years (range 60\u201392 years); median body mass index 21.7\u2009kg\/m<jats:sup>2<\/jats:sup>, median gait speed 0.67\u2009m\/s and 55% self\u2010reported their health status as fair or poor.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These findings suggest a more frail population in the <jats:styled-content style=\"fixed-case\">MILES<\/jats:styled-content> cohort compared with older adults in <jats:styled-content style=\"fixed-case\">USA<\/jats:styled-content> cohorts. <jats:styled-content style=\"fixed-case\">MILES<\/jats:styled-content> will provide estimates of burden of disease, and disability and risk factors in older adults. Findings will be used to identify potential interventions to prevent disability in this rural Indian population. <jats:bold>Geriatr Gerontol Int 2017; 17: 31\u201340.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.12668","type":"journal-article","created":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T09:08:43Z","timestamp":1450688923000},"page":"31-40","source":"Crossref","is-referenced-by-count":11,"title":["Design of the <scp>M<\/scp>obility and <scp>I<\/scp>ndependent <scp>L<\/scp>iving in <scp>E<\/scp>lders <scp>S<\/scp>tudy: An older adult cohort in rural <scp>I<\/scp>ndia"],"prefix":"10.1111","volume":"17","author":[{"given":"Tushar","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Epidemiology Graduate School of Public Health University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawan K","family":"Sharma","sequence":"additional","affiliation":[{"name":"SHARE INDIA, MediCiti Institute of Medical Sciences  RR District Telangana State India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guru Rajesh","family":"Jammy","sequence":"additional","affiliation":[{"name":"SHARE INDIA, MediCiti Institute of Medical Sciences  RR District Telangana State India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane A","family":"Cauley","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Graduate School of Public Health University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clareann H","family":"Bunker","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Graduate School of Public Health University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PS","family":"Reddy","sequence":"additional","affiliation":[{"name":"SHARE INDIA, MediCiti Institute of Medical Sciences  RR District Telangana State India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne B","family":"Newman","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Graduate School of Public Health University of Pittsburgh  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,21]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"GutmanG.Global aging: Key elements of the demographic transition.2011."},{"key":"e_1_2_7_3_1","unstructured":"KinsellK HeW.An aging world: 2008. 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