{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T17:26:27Z","timestamp":1775064387578,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,1,28]],"date-time":"2016-01-28T00:00:00Z","timestamp":1453939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of the present study was to investigate the prevalence of geriatric syndromes among older medical inpatients with atrial fibrillation, and their association with use of vitamin\u2009<jats:styled-content style=\"fixed-case\">K<\/jats:styled-content> antagonists.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study of patients aged \u226565 years discharged with a diagnosis of atrial fibrillation from the <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>cute <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>eriatric <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>ard was carried out. Stroke and bleeding risk were evaluated according to the <jats:styled-content style=\"fixed-case\">CHA<\/jats:styled-content><jats:sub>2<\/jats:sub><jats:styled-content style=\"fixed-case\">DS<\/jats:styled-content><jats:sub>2<\/jats:sub>\u2010<jats:styled-content style=\"fixed-case\">VASC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">HAS\u2010BLED<\/jats:styled-content> scores. Comorbidity, cognitive status, functional autonomy and contraindications to vitamin\u2009<jats:styled-content style=\"fixed-case\">K<\/jats:styled-content> antagonists were also considered.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Atrial fibrillation was documented in 1078 of 3650 patients (29.5%, mean age 83.4\u2009\u00b1\u20096.6 years, 60.3% women). Contraindications to vitamin\u2009<jats:styled-content style=\"fixed-case\">K<\/jats:styled-content> antagonists were documented in 24.9% of patients. Prescription of vitamin\u2009<jats:styled-content style=\"fixed-case\">K<\/jats:styled-content> antagonists at discharge was 37.8% and 47.9%, in the overall sample and in those without contraindications, respectively. In the overall sample, prescription of vitamin\u2009<jats:styled-content style=\"fixed-case\">K<\/jats:styled-content> antagonists was associated with younger age, permanent\/persistent atrial fibrillation, home discharge, less comorbidity, higher hemoglobin levels, better functional independence, known atrial fibrillation at admission and lower <jats:styled-content style=\"fixed-case\">HAS\u2010BLED<\/jats:styled-content> score. Among patients without contraindications to vitamin\u2009<jats:styled-content style=\"fixed-case\">K<\/jats:styled-content> antagonists, their use at discharge was independently associated with younger age, permanent\/persistent atrial fibrillation, home discharge, higher hemoglobin levels and <jats:styled-content style=\"fixed-case\">CHA<\/jats:styled-content>2<jats:styled-content style=\"fixed-case\">DS<\/jats:styled-content>2\u2010<jats:styled-content style=\"fixed-case\">VASC<\/jats:styled-content> score, better functional autonomy, and greater number of drugs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We showed a high prevalence of atrial fibrillation among older medical inpatients, who have a poor health status and a high prevalence of geriatric syndromes. Vitamin\u2009<jats:styled-content style=\"fixed-case\">K<\/jats:styled-content> antagonists were prescribed in less than half of the patients; underuse was mainly accounted for by a high prevalence of comorbidities\/contraindications, poor health status and limited functional autonomy. <jats:bold>Geriatr Gerontol Int 2017; 17: 416\u2013423.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.12730","type":"journal-article","created":{"date-parts":[[2016,1,28]],"date-time":"2016-01-28T10:22:52Z","timestamp":1453976572000},"page":"416-423","source":"Crossref","is-referenced-by-count":11,"title":["Health status, geriatric syndromes and prescription of oral anticoagulant therapy in elderly medical inpatients with atrial fibrillation"],"prefix":"10.1111","volume":"17","author":[{"given":"Mario","family":"Bo","sequence":"first","affiliation":[{"name":"SCDU Geriatria e Malattie Metaboliche dell'Osso Citt\u00e0 della Salute e della Scienza\u2010Molinette  Torino 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