{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T12:21:06Z","timestamp":1770553266073,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T00:00:00Z","timestamp":1499990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008990","name":"Science and Technology Department of Zhejiang Province","doi-asserted-by":"publisher","award":["No. 2014C33117"],"award-info":[{"award-number":["No. 2014C33117"]}],"id":[{"id":"10.13039\/501100008990","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Peroral endoscopic myotomy (POEM) has been proven to be effective for treating achalasia, but there are limited data on POEM in elderly patients. We therefore aimed to assess the role of POEM for achalasia in patients aged \u226560\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All consecutive patients that underwent POEM between December 2011 and November 2015 at a single center were retrospectively reviewed. Patients aged \u226560\u00a0years were assigned to group\u00a0A, whereas patients aged &lt;60\u00a0years were assigned to group\u00a0B. Demographic data, clinical data and treatment outcomes were compared between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the study period, 113 patients (18 in group\u00a0A, and 95 in group\u00a0B) were enrolled. The mean age of patients in group\u00a0A was 63\u00a0\u00b1\u00a03.9\u00a0years (range 60\u201374\u00a0years; 55.6% women), and that for patients in group\u00a0B was 37.7\u00a0\u00b1\u00a011.6\u00a0years (range 18\u201359\u00a0years; 42.2% women). The procedural time in group\u00a0A was similar to group\u00a0B (66.3\u00a0\u00b1\u00a033.3 <jats:italic>vs<\/jats:italic> 59.8\u00a0\u00b1\u00a024.2\u00a0min, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.332). There were also no significant differences in the incidence of intraoperative complications (<jats:italic>P<\/jats:italic>\u00a0=\u00a01.000) and gastroesophageal reflux rate (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.906) between the two groups. During the mean follow\u2010up period of 25.2\u00a0months, treatment success (Eckardt score \u22643) was achieved in 92.9% of patients in group\u00a0A, and 89.9% in group\u00a0B (<jats:italic>P<\/jats:italic>\u00a0=\u00a01.000).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>As well as in younger patients, POEM can be safely carried out in elderly patients, providing significant symptom relief. POEM might be recommended as the first therapeutic approach to elderly achalasia patients. <jats:bold>Geriatr Gerontol Int 2017; 17: 2407\u20132413<\/jats:bold>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.13083","type":"journal-article","created":{"date-parts":[[2017,7,14]],"date-time":"2017-07-14T05:14:35Z","timestamp":1500009275000},"page":"2407-2413","source":"Crossref","is-referenced-by-count":24,"title":["Peroral endoscopic myotomy is safe and effective in achalasia patients aged older than 60\u00a0years compared with younger patients"],"prefix":"10.1111","volume":"17","author":[{"given":"Xiaowei","family":"Tang","sequence":"first","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital Southern Medical University  Guangzhou China"},{"name":"Department of Gastroenterology, Hangzhou First People's Hospital Nanjing Medical University  Hangzhou 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Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital Southern Medical University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaofeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hangzhou First People's Hospital Nanjing Medical University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianfeng","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Hangzhou First People's Hospital Nanjing Medical University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengjie","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Beijing Tsinghua Changgung Hospital Medical Center Tsinghua University  Beijing 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