{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T00:12:48Z","timestamp":1793751168249,"version":"4.6.1"},"reference-count":30,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2018,9,16]],"date-time":"2018-09-16T00:00:00Z","timestamp":1537056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP15H05025"],"award-info":[{"award-number":["JP15H05025"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP16H05523"],"award-info":[{"award-number":["JP16H05523"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Previous studies have reported significant associations between tooth loss or periodontal status and cognitive function; however, animal experimental studies have shown that occlusion might be a more important factor in cognitive decline. The purpose of the present study was to investigate the influence of a lack of posterior occlusal support by residual teeth on the decline of cognitive function over a 3\u2010year period among 80\u2010year\u2010old Japanese people.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants were community\u2010dwelling older adults (<jats:italic>n<\/jats:italic>\u2009=\u2009515, age 79\u201381\u2009years). Cognitive function was measured using the Japanese version of the Montreal Cognitive Assessment. At baseline, participants were divided into two groups: those with and without posterior occlusal support. Participants whose Japanese version of the Montreal Cognitive Assessment score decreased by \u22653\u2009points over the 3\u2010year period were defined as the declined group. Logistic regression was carried out for the decline in Japanese version of the Montreal Cognitive Assessment scores, including dental status and possible risk factors as independent variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>More participants without posterior occlusal support tended to be in the cognitive decline group (49.4%) than in the maintained group (38.5%; \u03c7<jats:sup>2<\/jats:sup>\u2010test, <jats:italic>P<\/jats:italic>\u2009=\u20090.02). Logistic regression analysis showed that a lack of posterior occlusal support was a significant variable (odds ratio 1.55, <jats:italic>P<\/jats:italic>\u2009=\u20090.03) for cognitive decline, even after adjusting for other risk factors. However, the number of teeth or mean periodontal pocket depth was not significantly correlated with cognitive decline.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The present findings suggest that a lack of posterior occlusal support predicted the incidence of cognitive decline, even after adjusting for possible risk factors in community\u2010dwelling old\u2010old people. <jats:bold>Geriatr Gerontol Int 2018; 18: 1439\u20131446<\/jats:bold>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.13508","type":"journal-article","created":{"date-parts":[[2018,9,17]],"date-time":"2018-09-17T00:30:00Z","timestamp":1537144200000},"page":"1439-1446","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Influence of lack of posterior occlusal support on cognitive decline among 80\u2010year\u2010old Japanese people in a 3\u2010year prospective study"],"prefix":"10.1111","volume":"18","author":[{"given":"Kodai","family":"Hatta","sequence":"first","affiliation":[{"name":"Department of Prosthodontics, Gerodontology and Oral Rehabilitation Osaka University Graduate School of Dentistry  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5696-6785","authenticated-orcid":false,"given":"Kazunori","family":"Ikebe","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Gerodontology and Oral Rehabilitation Osaka University Graduate School of Dentistry  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuyuki","family":"Gondo","sequence":"additional","affiliation":[{"name":"Department of Clinical Thanatology and Geriatric Behavioral Science Osaka University Graduate School of Human Sciences  Osaka 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