{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T23:26:20Z","timestamp":1780442780350,"version":"3.54.1"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,12,14]],"date-time":"2018-12-14T00:00:00Z","timestamp":1544745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>We investigated the clinical characteristics and short\u2010term outcomes in acute cholecystitis (AC) patients aged \u226580 years. We therefore sought to determine the ideal treatment for elderly patients with AC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively evaluated 253 patients with AC. The patients were divided into two groups according to their age: elderly group (<jats:italic>n<\/jats:italic> = 77, aged \u226580 years) and non\u2010elderly group (<jats:italic>n<\/jats:italic> = 176, aged &lt;80 years). We compared the clinical characteristics, in\u2010hospital mortality and recurrence of cholecystitis within 6 months between the two groups. The predictive factors for in\u2010hospital mortality were also assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The elderly group had more severe comorbidities (<jats:italic>P<\/jats:italic> = 0.0055), higher severity grade of AC (<jats:italic>P<\/jats:italic> = 0.00071) and higher in\u2010hospital mortality (<jats:italic>P<\/jats:italic> = 0.029) than the non\u2010elderly group. The multivariate analysis showed that the serum creatinine level (hazard ratio 12.43; <jats:italic>P<\/jats:italic> = 0.002) was independently associated with the in\u2010hospital mortality. The elderly group (20.8%) underwent subsequent cholecystectomy less frequently than the non\u2010elderly group (63.2%; <jats:italic>P<\/jats:italic> &lt; 0.0001). The recurrence rate of AC was comparable between the two groups (<jats:italic>P<\/jats:italic> = 0.89). The proportion of patients in the elderly group who received percutaneous drainage in the latter period (64.3%) was significantly higher than in the former period (33.3%; <jats:italic>P<\/jats:italic> = 0.015).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>More attention should be paid to AC patients with chronic renal disease after treatment. Percutaneous drainage might serve as a definitive treatment without subsequent cholecystectomy in elderly AC patients with various comorbidities. <jats:bold>Geriatr Gerontol Int 2019; 19: 208\u2013212<\/jats:bold>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.13588","type":"journal-article","created":{"date-parts":[[2018,12,14]],"date-time":"2018-12-14T08:15:08Z","timestamp":1544775308000},"page":"208-212","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Clinical characteristics and short\u2010term outcomes in patients with acute cholecystitis over aged &gt;80 years"],"prefix":"10.1111","volume":"19","author":[{"given":"Takafumi","family":"Akasu","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6546-4485","authenticated-orcid":false,"given":"Akiyoshi","family":"Kinoshita","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nami","family":"Imai","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Hirose","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruri","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeharu","family":"Yokota","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Iwaku","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhiko","family":"Koike","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology The Jikei University Daisan Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Saruta","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Department of Internal Medicine The Jikei University School of Medicine  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.08.045"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.138.5.531"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.sle.0000191619.02145.c0"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6215-13-7"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.8836"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLE.0b013e318171525d"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.13330"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-015-0361-0"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000455241"},{"key":"e_1_2_7_11_1","unstructured":"Ministry of Health Labor and Welfare 2016. 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