{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T20:19:58Z","timestamp":1793996398703,"version":"4.8.0"},"reference-count":28,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,7,24]],"date-time":"2019-07-24T00:00:00Z","timestamp":1563926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the prevalence rate and factors associated with sarcopenia in Japanese patients with rheumatoid arthritis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We enrolled 240 consecutive patients with rheumatoid arthritis aged \u226565\u2009years in this study. We examined clinical data: age, sex, body mass index, disease duration, rheumatoid factor positivity, anti\u2010cyclic citrullinated peptide antibody positivity, biological or target synthetic disease\u2010modifying antirheumatic drug use, methotrexate use, glucocorticoid use, C\u2010reactive protein level, disease activity score in 28 joints\u2010erythrocyte sedimentation rate, Health Assessment Questionnaire Disability Index, bone mineral density of the lumbar spine and total hip, grip strength, gait speed, and relative skeletal muscle mass index by bioelectrical impedance analysis. Sarcopenia was defined according to a consensus report by the Asian Working Group for Sarcopenia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence rate of sarcopenia was found to be 29.6%. Multivariate analysis identified the following factors to be associated with sarcopenia: age (<jats:italic>P<\/jats:italic> = 0.008; odds ratio 1.08), body mass index (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001; odds ratio 0.73), C\u2010reactive protein (<jats:italic>P<\/jats:italic> = 0.017; odds ratio 1.76) and hip bone mineral density (<jats:italic>P<\/jats:italic> = 0.037; odds ratio 0.61).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The sarcopenia\u2010associated factors were age, body mass index, C\u2010reactive protein and hip bone mineral density in Japanese patients with rheumatoid arthritis. Because the Health Assessment Questionnaire Disability Index, a standard measurement of function, cannot predict sarcopenia, the muscle mass needs to be measured while assessing changes in grip strength, body mass index, C\u2010reactive protein and hip bone mineral density. <jats:bold>Geriatr Gerontol Int 2019; 19: 907\u2013912<\/jats:bold>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.13747","type":"journal-article","created":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T04:58:30Z","timestamp":1564030710000},"page":"907-912","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":73,"title":["Sarcopenia\u2010associated factors in Japanese patients with rheumatoid arthritis: A cross\u2010sectional study"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8316-8671","authenticated-orcid":false,"given":"Takeshi","family":"Mochizuki","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery Kamagaya General Hospital  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichiro","family":"Yano","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Tokyo Women's Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsunori","family":"Ikari","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Tokyo Women's Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Okazaki","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Tokyo Women's Medical University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,7,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afq034"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.12998"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.10897"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/03009740500327727"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/03009740510018633"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2011.01.003"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afy169"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2013.11.025"},{"key":"e_1_2_6_10_1","first-page":"65","article-title":"The American rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis","volume":"16","author":"Arnett FC","year":"1988","journal-title":"Arthritis Rheum"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.27584"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780230202"},{"key":"e_1_2_6_13_1","first-page":"167","article-title":"The Stanford health assessment questionnaire: A review of its history, issues, progress, and documentation","volume":"30","author":"Bruce B","year":"2003","journal-title":"J Rheumatol"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0899-9007(98)00171-3"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/30.3.221"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-017-3665-x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.5152\/eurjrheum.2015.0038"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.12674"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2000.tb06515.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2010.05.005"},{"key":"e_1_2_6_21_1","first-page":"1505","article-title":"Rheumatoid cachexia: depletion of lean body mass in rheumatoid arthritis. 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