{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T19:17:16Z","timestamp":1792610236146,"version":"4.5.0"},"reference-count":32,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T00:00:00Z","timestamp":1689638400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Advances in laparoscopic surgery and perioperative care have improved the prognosis of operated patients, especially the oldest among them. This study aimed to assess the outcomes of early laparoscopic cholecystectomy for acute calculous cholecystitis in older adult patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis was carried out of 567 patients who underwent early laparoscopic cholecystectomy for acute calculous cholecystitis between January 2003 and July 2021. The outcomes of older adult patients (\u2265\u200975\u2009years) were compared with those of younger patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The older adult group had significantly more patients with an American Society of Anesthesiologists score\u2009\u22653 (37.5% <jats:italic>vs<\/jats:italic> 8.3%; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001) and more severe acute calculous cholecystitis (grade II; 82.8% <jats:italic>vs<\/jats:italic> 67%; <jats:italic>P<\/jats:italic>\u2009=\u20090.01). There were no significant differences regarding operative time (90 <jats:italic>vs<\/jats:italic> 80\u2009min; <jats:italic>P<\/jats:italic>\u2009=\u20090.064), conversion rate (20.3% <jats:italic>vs<\/jats:italic> 13.5%; <jats:italic>P<\/jats:italic>\u2009=\u20090.144), and both intra\u2010 and postoperative morbidity, principally bile duct injuries (1.6% <jats:italic>vs<\/jats:italic> 0%; <jats:italic>P<\/jats:italic>\u2009=\u20090.113) and bile leakage (0% <jats:italic>vs<\/jats:italic> 1.2%; <jats:italic>P<\/jats:italic>\u2009=\u20091).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Early laparoscopic cholecystectomy could be proposed safely for older adult patients with mild and moderate acute cholecystitis. <jats:bold>Geriatr Gerontol Int 2023; 23: 671\u2013675<\/jats:bold>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.14643","type":"journal-article","created":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T23:53:38Z","timestamp":1689724418000},"page":"671-675","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Early laparoscopic cholecystectomy for acute cholecystitis: Does age matter?"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7535-4773","authenticated-orcid":false,"given":"Malek","family":"Barka","sequence":"first","affiliation":[{"name":"Department of General and Digestive Surgery Farhat Hached University Hospital, Faculty of Medicine of Sousse  Sousse Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Salah","family":"Jarrar","sequence":"additional","affiliation":[{"name":"Department of General and Digestive Surgery Farhat Hached University Hospital, Faculty of Medicine of Sousse  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